Vistaril and Levothroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Levothroid (levothyroxine sodium). Common drug interactions include fibromyalgia among females and tremor among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Levothroid. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.



On Jul, 11, 2026

38 people who take Vistaril and Levothroid together, and have interactions are studied.

Vistaril and Levothroid drug interactions.

What are the common drug interactions of Vistaril and Levothroid, by gender? *:

female:

  1. Fibromyalgia (a long-term condition which causes pain all over the body)
  2. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  3. Pain in extremity
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Spinal osteoarthritis (joint cartilage loss in spine)
  6. Suicidal ideation
  7. Weight decreased
  8. Ankle fracture
  9. Arteriosclerosis (thickening and hardening of arteries)
  10. Bone pain

male:

  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Abdominal adhesions (inflammation of abdomen)
  3. Asthma
  4. Attention deficit/hyperactivity disorder
  5. Autonomic failure syndrome (a degenerative disease of the autonomic nervous system)
  6. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  7. Blood glucose fluctuation
  8. Cardiac amyloidosis (protein deposition in heart)
  9. Cardiolipin antibody positive
  10. Cerebellar ataxia (loss of coordination)

What are the common drug interactions of Vistaril and Levothroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Acute hepatic failure
  2. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  3. Hepatotoxicity (chemical-driven liver damage)
  4. Overdose

30-39:

n/a

40-49:

  1. Suicidal ideation
  2. Alopecia (absence of hair from areas of the body)
  3. Arteriosclerosis (thickening and hardening of arteries)
  4. Arthralgia (joint pain)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Asthenia (weakness)
  7. Back pain
  8. Bone pain
  9. Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
  10. Breast cancer

50-59:

  1. Palpitations (feelings or sensations that your heart is pounding or racing)
  2. Pruritus (severe itching of the skin)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Weakness
  6. Arthralgia (joint pain)
  7. Back pain
  8. Cardiac arrest
  9. Chest pain
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Dizziness
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Alopecia (absence of hair from areas of the body)
  4. Dyspnoea (difficult or laboured respiration)
  5. Renal failure (kidney dysfunction)
  6. Anaemia (lack of blood)
  7. Blood pressure increased
  8. Chronic kidney disease
  9. Confusional state
  10. Diarrhoea

What are the existing conditions these people have? *

  1. Pain: 13 people, 34.21%
  2. Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 18.42%
  3. Spinal Osteoarthritis (joint cartilage loss in spine): 7 people, 18.42%
  4. Neuropathy Peripheral (surface nerve damage): 6 people, 15.79%
  5. Abdominal Discomfort: 5 people, 13.16%
  6. Nausea (feeling of having an urge to vomit): 5 people, 13.16%
  7. Fever: 5 people, 13.16%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 13.16%
  9. Headache (pain in head): 5 people, 13.16%
  10. Hypersensitivity: 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vistaril and Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vistaril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levothroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride and levothyroxine sodium (the active ingredients of Vistaril and Levothroid, respectively), and Vistaril and Levothroid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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