Vistaril and Minipress drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Minipress (prazosin hydrochloride). Common drug interactions include drug ineffective among females and parasomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Minipress. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Minipress?

Minipress has active ingredients of prazosin hydrochloride. It is often used in post-traumatic stress disorder. eHealthMe is studying from 2,213 Minipress users. Check the latest studies of Minipress.

On Aug, 01, 2026

27 people who take Vistaril and Minipress together, and have interactions are studied.

Vistaril and Minipress drug interactions.

What are the common drug interactions of Vistaril and Minipress, by gender? *:

female:

Drug ineffective
Pain
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Suicide attempt
Weight decreased
Alopecia (absence of hair from areas of the body)
Pneumonia
Pulmonary oedema (fluid accumulation in the lungs)
Suicidal ideation
Aggression

male:

Parasomnia (sleep disorders that involve abnormal and unnatural movements, behaviours, emotions, perceptions)
Abnormal behaviour
Weight decreased
White blood cell count decreased
Cardiac arrest
Drug abuse
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Energy increased
Loss of consciousness
Psychotic disorder

What are the common drug interactions of Vistaril and Minipress, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Parasomnia (sleep disorders that involve abnormal and unnatural movements, behaviours, emotions, perceptions)
Abdominal pain upper
Ill-defined disorder
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Vertigo
Vomiting

30-39:

Drug ineffective
Pain
Acute myocardial infarction (acute heart attack)
Back pain
Bipolar disorder (mood disorder)
Cardiac arrest
Circulatory collapse
Drug abuse
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dyspnoea (difficult or laboured respiration)

40-49:

Aggression
Aura
Confusional state
Mass
Memory impairment
Migraine (headache)
Neoplasm (tumour)
Aphonia (inability to produce voice)
Cardiac valve disease (heart valve disease)
Dry throat

50-59:

Adverse event
Dissociation
Energy increased
Sedation

60+:

Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Suicide attempt
Weight decreased
Cardiac arrest
Chronic kidney disease
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Depression: 5 people, 18.52%
Bipolar Disorder (mood disorder): 5 people, 18.52%
Nightmares (unpleasant dreams): 3 people, 11.11%
High Blood Pressure: 3 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
Asthma: 3 people, 11.11%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 7.41%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 7.41%
Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 2 people, 7.41%
Pain: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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