Vistaril and Oxybutynin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Oxybutynin (oxybutynin). Common drug interactions include neuralgia among females and back injury among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Oxybutynin. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Oxybutynin?

Oxybutynin has active ingredients of oxybutynin. It is often used in urge incontinence. eHealthMe is studying from 23,143 Oxybutynin users. Check the latest studies of Oxybutynin.

On Jul, 20, 2026

37 people who take Vistaril and Oxybutynin together, and have interactions are studied.

Vistaril and Oxybutynin drug interactions.

What are the common drug interactions of Vistaril and Oxybutynin, by gender? *:

female:

Neuralgia (pain in one or more nerves)
Neurological symptom (symptoms of nervous system disease)
Oedema peripheral (superficial swelling)
Oral candidiasis (fungal infection of mouth)
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Pneumonia
Chronic kidney disease

male:

Back injury
Brain injury
Traumatic haematoma (a blood clot in body due to trauma)
Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Bladder spasm
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Constipation
Haemorrhage (bleeding)

What are the common drug interactions of Vistaril and Oxybutynin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Traumatic haematoma (a blood clot in body due to trauma)
Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Chronic kidney disease
Crying
Haemorrhage (bleeding)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertension (high blood pressure)
Renal failure (kidney dysfunction)
Screaming (a long loud piercing cry)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Sepsis (a severe blood infection that can lead to organ failure and death)
Nephrogenic anaemia (anaemia due to kidney disease)
Alopecia (absence of hair from areas of the body)
Bipolar disorder (mood disorder)
Death
Hair colour changes
Hair disorder

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Back pain
Nephrogenic anaemia (anaemia due to kidney disease)
Urinary tract infection
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Bone disorder
Bone pain

60+:

Myalgia (muscle pain)
Rectal cancer (cancer of rectum)
Dizziness
Dry mouth
Fatigue (feeling of tiredness)
Gait disturbance
Head discomfort
Hypotension (abnormally low blood pressure)
Irritability
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 37.84%
High Blood Pressure: 13 people, 35.14%
High Blood Cholesterol: 12 people, 32.43%
Pain: 8 people, 21.62%
Multiple Allergies (allergy to multiple agents): 6 people, 16.22%
Depression: 6 people, 16.22%
Infection: 5 people, 13.51%
Incontinence (lack of moderation or self-control): 5 people, 13.51%
Inflammation: 4 people, 10.81%
Neuralgia (pain in one or more nerves): 4 people, 10.81%

* Approximation only. Some reports may have incomplete information.

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