Vistaril and Robinul drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Robinul (glycopyrrolate). Common drug interactions include cognitive disorder among females and blood creatinine increased among males.
The phase IV clinical study analyzes what interactions people have when they take Vistaril and Robinul. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Vistaril?
Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.
What is Robinul?
Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.
20 people who take Vistaril and Robinul together, and have interactions are studied.

What are the common drug interactions of Vistaril and Robinul, by gender? *:
female:
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Headache (pain in head)
- Hypertension (high blood pressure)
- Hypertensive crisis
- Hypokalaemia (low potassium)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Abdominal pain
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cholecystitis acute (rapid infection of gallbladder)
- Depression
male:
- Blood creatinine increased
- Acute lymphocytic leukaemia (cancer of the white blood cells)
- Coagulopathy (blood's ability to clot is impaired)
- Confusional state
- Cough
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Delirium (wild excitement)
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Electrocardiogram qt prolonged
What are the common drug interactions of Vistaril and Robinul, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Liver injury
- Malignant neoplasm progression (cancer tumour came back)
- Neuropathy peripheral (surface nerve damage)
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Oedema peripheral (superficial swelling)
- Pancreatic enlargement
- Pancreatitis (inflammation of pancreas)
- Pericardial effusion (fluid around the heart)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Pyrexia (fever)
20-29:
- Pain
30-39:
- Post-operative pain
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Pulmonary embolism (blockage of the main artery of the lung)
- Constipation
- Seroma (a tumour like collection of serum in the tissues)
- Wound dehiscence (a surgical incision reopens either internally or externally)
40-49:
- Headache (pain in head)
- Hypertension (high blood pressure)
- Hypertensive crisis
- Hypokalaemia (low potassium)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Abdominal pain
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Blood creatinine increased
- Bone density decreased
50-59:
- Pain
60+:
- International normalised ratio increased
- Respiratory depression (respiration has a rate below 12 breaths)
What are the existing conditions these people have? *
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 25.00%
- Hiv Infection: 2 people, 10.00%
- Pain: 1 person, 5.00%
- Nausea And Vomiting: 1 person, 5.00%
- Nausea (feeling of having an urge to vomit): 1 person, 5.00%
- Muscle Spasms (muscle contraction): 1 person, 5.00%
- Gastric Disorder (disease of stomach): 1 person, 5.00%
- Depression: 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Vistaril and Robinul?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vistaril and Robinul:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vistaril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Robinul:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vistaril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Robinul and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on hydroxyzine hydrochloride and glycopyrrolate (the active ingredients of Vistaril and Robinul, respectively), and Vistaril and Robinul (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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