Vistaril and Sucralfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Sucralfate (sucralfate). Common drug interactions include dermatitis exfoliative among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Sucralfate. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Sucralfate?

Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

58 people who take Vistaril and Sucralfate together, and have interactions are studied.

Vistaril and Sucralfate drug interactions.

What are the common drug interactions of Vistaril and Sucralfate, by gender? *:

female:

  1. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  2. Dry mouth
  3. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  4. Haemoglobin decreased
  5. Photosensitivity reaction
  6. Platelet count decreased
  7. Rash pruritic (redness with itching)
  8. Renal failure (kidney dysfunction)
  9. Vomiting
  10. Suicide attempt

male:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Depression
  4. Headache (pain in head)
  5. Nephrolithiasis (calculi in the kidneys)
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  7. Abdominal distension
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Cellulitis (infection under the skin)
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Vistaril and Sucralfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  2. Depression
  3. Fear
  4. Headache (pain in head)
  5. Loss of employment
  6. Morbid thoughts (serious thoughts)
  7. Muscle twitching
  8. Panic attack
  9. Quality of life decreased
  10. Suicidal ideation

30-39:

  1. Cough
  2. Injection site erythema (redness at injection site)
  3. Injection site rash
  4. Pyrexia (fever)
  5. Viral infection
  6. Dissociation
  7. Injection site bruising
  8. Injection site pain
  9. Injection site warmth
  10. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Nausea (feeling of having an urge to vomit)
  4. Renal tubular necrosis (death of kidney tubules)
  5. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Confusional state
  8. Dehydration (dryness resulting from the removal of water)
  9. Diarrhoea
  10. Vomiting

50-59:

  1. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  2. Dizziness
  3. Dyspnoea (difficult or laboured respiration)
  4. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  5. Fluid overload (too much fluid in the blood)
  6. Haemoglobin decreased
  7. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  8. Hyperkalaemia (damage to or disease of the kidney)
  9. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  10. Hypocalcaemia (levels of calcium in blood serum are abnormally low)

60+:

  1. Headache (pain in head)
  2. Chest pain
  3. Dry mouth
  4. Dyspnoea (difficult or laboured respiration)
  5. Epistaxis (bleed from the nose)
  6. Gastritis (inflammation of stomach)
  7. Hypertension (high blood pressure)
  8. Hypotension (abnormally low blood pressure)
  9. Malignant neoplasm progression (cancer tumour came back)
  10. Memory impairment

What are the existing conditions these people have? *

  1. Pain: 10 people, 17.24%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 12.07%
  3. High Blood Pressure: 7 people, 12.07%
  4. Sleep Disorder: 6 people, 10.34%
  5. Pulmonary Embolism (blockage of the main artery of the lung): 5 people, 8.62%
  6. Dehydration (dryness resulting from the removal of water): 5 people, 8.62%
  7. Nausea (feeling of having an urge to vomit): 4 people, 6.90%
  8. Gastritis (inflammation of stomach): 4 people, 6.90%
  9. Depression: 4 people, 6.90%
  10. Asthma: 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vistaril and Sucralfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sucralfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vistaril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sucralfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride and sucralfate (the active ingredients of Vistaril and Sucralfate, respectively), and Vistaril and Sucralfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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