Vistaril and Sumatriptan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Sumatriptan (sumatriptan succinate). Common drug interactions include flushing among females.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Sumatriptan. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

On Jul, 21, 2026

19 people who take Vistaril and Sumatriptan together, and have interactions are studied.

Vistaril and Sumatriptan drug interactions.

What are the common drug interactions of Vistaril and Sumatriptan, by gender? *:

female:

Flushing (the warm, red condition of human skin)
Alanine aminotransferase increased
Anger
Aphonia (inability to produce voice)
Blindness transient (sudden loss of vision)
Concussion (short loss of normal brain function in response to a head injury)
Depression
Diarrhoea
Diplopia (double vision)
Dissociation

male:

n/a

What are the common drug interactions of Vistaril and Sumatriptan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Diarrhoea
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Impaired work ability
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pulmonary oedema (fluid accumulation in the lungs)
Unresponsive to stimuli

30-39:

Abortion spontaneous (naturally occurring miscarriage)
Dissociation
Maternal exposure during pregnancy (use of substance during pregnancy)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Syncope (loss of consciousness with an inability to maintain postural tone)

40-49:

Anger
Aphonia (inability to produce voice)
Blindness transient (sudden loss of vision)
Fatigue (feeling of tiredness)
Feeling hot
Flushing (the warm, red condition of human skin)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Panic attack
Post-traumatic stress disorder

50-59:

Depression
Dizziness
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Fall
Fatigue (feeling of tiredness)
Fracture
Hypotension (abnormally low blood pressure)
Injury
Memory impairment
Nephrogenic anaemia (anaemia due to kidney disease)

60+:

Acute respiratory failure
Diplopia (double vision)
Headache (pain in head)
Pneumonia bacterial (pneumonia associated with bacterial infection)

What are the existing conditions these people have? *

Pain: 5 people, 26.32%
Gait Disturbance: 2 people, 10.53%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 10.53%
Constipation: 2 people, 10.53%
Sleep Disorder: 2 people, 10.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.53%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.26%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 5.26%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 1 person, 5.26%
Depression: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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