Vitamin b1 and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin b1 (thiamine) and Codeine (codeine sulfate). Common drug interactions include drug ineffective among females and syncope among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin b1 and Codeine. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin b1?

Vitamin b1 has active ingredients of thiamine. It is often used in fatigue. eHealthMe is studying from 4,662 Vitamin b1 users. Check the latest studies of Vitamin b1.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 15, 2026

36 people who take Vitamin b1 and Codeine together, and have interactions are studied.

Vitamin b1 and Codeine drug interactions.

What are the common drug interactions of Vitamin B1 and Codeine, by gender? *:

female:

  1. Drug ineffective
  2. Vomiting
  3. Headache (pain in head)
  4. Drug intolerance (drug sensitivity)
  5. Abdominal discomfort
  6. Hypersensitivity
  7. Blood magnesium decreased
  8. Nausea (feeling of having an urge to vomit)
  9. Diarrhoea
  10. Angioedema (rapid swelling of the dermis)

male:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Fall
  3. Diarrhoea
  4. Haematochezia (passage of stools containing blood)
  5. Liver disorder (liver diseases)
  6. Pneumonia
  7. Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
  8. Hypotension (abnormally low blood pressure)
  9. Loss of consciousness
  10. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the common drug interactions of Vitamin B1 and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  2. Sinusitis (inflammation of sinus)
  3. Sleep disorder due to general medical condition, insomnia type (a conditions that prevent a person from getting restful sleep due to mental condition of not getting sleep)
  4. Stomatitis (inflammation of mucous membrane of mouth)
  5. Urticaria (rash of round, red welts on the skin that itch intensely)
  6. Weight increased
  7. Anti-cyclic citrullinated peptide antibody positive
  8. Arthropathy
  9. Asthma
  10. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)

50-59:

n/a

60+:

  1. Blood magnesium decreased
  2. Diarrhoea
  3. Catheter site erythema (redness of skin at catheter site)
  4. Catheter site related reaction
  5. Gastric dilatation (a twisted stomach)
  6. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  7. Blood potassium decreased
  8. Electrolyte imbalance
  9. Abdominal discomfort
  10. Device related infection

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 30.56%
  2. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 10 people, 27.78%
  3. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 10 people, 27.78%
  4. Nausea (feeling of having an urge to vomit): 10 people, 27.78%
  5. Haemoglobin Decreased: 10 people, 27.78%
  6. Headache (pain in head): 9 people, 25.00%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 25.00%
  8. Indigestion: 9 people, 25.00%
  9. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 9 people, 25.00%
  10. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin b1 and Codeine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vitamin b1 and Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin b1:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin b1 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Codeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on thiamine and codeine sulfate (the active ingredients of Vitamin b1 and Codeine, respectively), and Vitamin b1 and Codeine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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