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Vitamin b6 and Gocovri drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin b6 (pyridoxine) and Gocovri (amantadine hydrochloride). Common drug interactions include dry mouth among females and deep brain stimulation among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin b6 and Gocovri. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin b6?

Vitamin b6 has active ingredients of pyridoxine. It is often used in stress and anxiety. eHealthMe is studying from 16,183 Vitamin b6 users. Check the latest studies of Vitamin b6.

What is Gocovri?

Gocovri has active ingredients of amantadine hydrochloride. eHealthMe is studying from 2,662 Gocovri users. Check the latest studies of Gocovri.

On Jul, 19, 2026

16 people who take Vitamin b6 and Gocovri together, and have interactions are studied.

Vitamin b6 and Gocovri drug interactions.

What are the common drug interactions of Vitamin B6 and Gocovri, by gender? *:

female:

  1. Dry mouth
  2. Nervousness
  3. Dry eye (lack of adequate tears)
  4. Erythema (redness of the skin)
  5. Speech disorder
  6. Weight decreased
  7. Balance disorder
  8. Abdominal distension
  9. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  10. Constipation

male:

  1. Deep brain stimulation
  2. Parkinson's disease
  3. Death
  4. Colostomy
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Abnormal dreams
  7. Fall
  8. Hallucination (an experience involving the perception of something not present)
  9. Insomnia (sleeplessness)
  10. Weight increased

What are the common drug interactions of Vitamin B6 and Gocovri, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Dry mouth
  2. Nervousness
  3. Balance disorder
  4. Abdominal distension
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Death
  7. Device dislocation
  8. Discomfort
  9. Gait disturbance
  10. Gastrointestinal tract irritation

What are the existing conditions these people have? *

  1. Parkinson's Disease: 9 people, 56.25%
  2. Dyskinesia (abnormality or impairment of voluntary movement): 8 people, 50.00%
  3. Urinary Tract Disorder: 1 person, 6.25%
  4. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 6.25%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  6. On And Off Phenomenon: 1 person, 6.25%
  7. Mood Swings (an extreme or rapid change in mood): 1 person, 6.25%
  8. Incontinence (lack of moderation or self-control): 1 person, 6.25%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 6.25%
  10. Depression: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin b6 and Gocovri?

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- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vitamin b6 and Gocovri:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin b6:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gocovri:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin b6 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gocovri and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on pyridoxine and amantadine hydrochloride (the active ingredients of Vitamin b6 and Gocovri, respectively), and Vitamin b6 and Gocovri (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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