Vitamin d and Oxymetazoline hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin d (ergocalciferol) and Oxymetazoline hydrochloride (oxymetazoline hydrochloride). Common drug interactions include epistaxis among females and bipolar disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin d and Oxymetazoline hydrochloride. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin d?

Vitamin d has active ingredients of ergocalciferol. It is often used in low vitamin d. eHealthMe is studying from 294,094 Vitamin d users. Check the latest studies of Vitamin d.

What is Oxymetazoline hydrochloride?

Oxymetazoline hydrochloride has active ingredients of oxymetazoline hydrochloride. eHealthMe is studying from 594 Oxymetazoline hydrochloride users. Check the latest studies of Oxymetazoline hydrochloride.



On Jul, 07, 2026

71 people who take Vitamin d and Oxymetazoline hydrochloride together, and have interactions are studied.

Vitamin d and Oxymetazoline hydrochloride drug interactions.

What are the common drug interactions of Vitamin D and Oxymetazoline Hydrochloride, by gender? *:

female:

  1. Epistaxis (bleed from the nose)
  2. Eye pruritus (eye itching)
  3. Feeling hot
  4. Food allergy
  5. Food interaction
  6. Gastritis (inflammation of stomach)
  7. Headache (pain in head)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Infection
  10. Infusion site erythema (reddening of the skin at infusion site)

male:

  1. Bipolar disorder (mood disorder)
  2. Dehydration (dryness resulting from the removal of water)
  3. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  4. Cardiomyopathy (weakening of the heart muscle)
  5. Depression
  6. Drug ineffective
  7. Fatigue (feeling of tiredness)
  8. Nausea (feeling of having an urge to vomit)
  9. Pneumonia
  10. Influenza

What are the common drug interactions of Vitamin D and Oxymetazoline Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Lower limb fracture

30-39:

  1. Hypersensitivity
  2. Cough
  3. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

40-49:

  1. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  2. White blood cell count decreased
  3. Anxiety
  4. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
  5. Cough
  6. Dry eye (lack of adequate tears)
  7. Eye pruritus (eye itching)
  8. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  9. Arthralgia (joint pain)
  10. Bone pain

50-59:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Drug ineffective
  3. Influenza
  4. Intervertebral disc disorder (spinal disc disorder)
  5. Nausea (feeling of having an urge to vomit)
  6. Nephrolithiasis (calculi in the kidneys)
  7. Pain
  8. Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
  9. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  10. Stress

60+:

  1. Fall
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Hordeolum (small collection of pus (abscess) on the eyelid)
  4. Hypersensitivity
  5. Memory impairment
  6. Pneumonia
  7. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  8. Post procedural cellulitis (post procedural bacterial infection of the skin and soft tissues)
  9. Seasonal allergy (allergic condition due to certain season)
  10. Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 12 people, 16.90%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 14.08%
  3. Pain: 7 people, 9.86%
  4. High Blood Pressure: 7 people, 9.86%
  5. High Blood Cholesterol: 6 people, 8.45%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.45%
  7. Depression: 5 people, 7.04%
  8. Cough: 5 people, 7.04%
  9. Type 2 Diabetes: 4 people, 5.63%
  10. Renal Cell Carcinoma (a kidney cancer): 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin d and Oxymetazoline hydrochloride?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vitamin d and Oxymetazoline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oxymetazoline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin d and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxymetazoline hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol and oxymetazoline hydrochloride (the active ingredients of Vitamin d and Oxymetazoline hydrochloride, respectively), and Vitamin d and Oxymetazoline hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: