Voltaren and Amoxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Amoxil (amoxicillin). Common drug interactions include diabetic retinopathy among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Amoxil. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Amoxil?

Amoxil has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 3,641 Amoxil users. Check the latest studies of Amoxil.



On Jul, 19, 2026

52 people who take Voltaren and Amoxil together, and have interactions are studied.

Voltaren and Amoxil drug interactions.

What are the common drug interactions of Voltaren and Amoxil, by gender? *:

female:

  1. Diabetic retinopathy (damage to the retina caused by complications of diabetes)
  2. Dizziness postural
  3. Episcleritis (acute inflammatory disorder of the episclera of eye)
  4. Eye haemorrhage (bleeding in the eye)
  5. Eye pain
  6. Fatigue (feeling of tiredness)
  7. Gamma-glutamyltransferase increased
  8. Headache (pain in head)
  9. Lymphocyte count decreased
  10. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)

male:

  1. Cellulitis (infection under the skin)
  2. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  3. Hallucination, auditory (perceiving sounds without auditory stimulus)
  4. Impaired self-care
  5. Judgement impaired
  6. Monocyte count decreased
  7. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  10. Poor quality sleep

What are the common drug interactions of Voltaren and Amoxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  2. Haematocrit decreased
  3. Pancreatitis acute (sudden inflammation of pancreas)
  4. Sinus bradycardia (an unusually slow heartbeat due to heart disease)
  5. Skin lesion
  6. Vaginitis bacterial (inflammation of the vagina caused by bacterial infection)

40-49:

  1. Episcleritis (acute inflammatory disorder of the episclera of eye)
  2. Eye haemorrhage (bleeding in the eye)
  3. Eye pain
  4. Fatigue (feeling of tiredness)
  5. Gamma-glutamyltransferase increased
  6. Headache (pain in head)
  7. Lymphocyte count decreased
  8. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  10. Psoriasis (immune-mediated disease that affects the skin)

50-59:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Renal failure (kidney dysfunction)
  4. Oesophageal stenosis (narrowing of oesophagus)

60+:

  1. Haemoglobin decreased
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Anal cancer
  4. Angioedema (rapid swelling of the dermis)
  5. Anxiety
  6. Arteriosclerosis (thickening and hardening of arteries)
  7. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  8. Asthenia (weakness)
  9. Back pain
  10. Bacterial infection

What are the existing conditions these people have? *

  1. Pain: 18 people, 34.62%
  2. Diabetes: 10 people, 19.23%
  3. Stress And Anxiety: 9 people, 17.31%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 17.31%
  5. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 8 people, 15.38%
  6. Nausea (feeling of having an urge to vomit): 7 people, 13.46%
  7. Depression: 7 people, 13.46%
  8. Muscle Aches (muscle pain): 6 people, 11.54%
  9. Bipolar Disorder (mood disorder): 5 people, 9.62%
  10. Cardiac Disorder: 5 people, 9.62%

* Approximation only. Some reports may have incomplete information.

Do you take Voltaren and Amoxil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Voltaren and Amoxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Voltaren:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amoxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Voltaren and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amoxil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium and amoxicillin (the active ingredients of Voltaren and Amoxil, respectively), and Voltaren and Amoxil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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