Voltaren and Claforan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Claforan (cefotaxime sodium). Common drug interactions include neutropenia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Claforan. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Claforan?

Claforan has active ingredients of cefotaxime sodium. eHealthMe is studying from 2,527 Claforan users. Check the latest studies of Claforan.

On Jul, 08, 2026

17 people who take Voltaren and Claforan together, and have interactions are studied.

Voltaren and Claforan drug interactions.

What are the common drug interactions of Voltaren and Claforan, by gender? *:

female:

Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Surgery
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatinine increased
Candida sepsis (candida in blood stream)
Catheter related infection
Cerebral infarction (less blood supply to brain resulting tissue damage)
Conjunctivitis (pink eye)
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)

male:

Pyrexia (fever)
Erythema (redness of the skin)
C-reactive protein increased
Rash
Brain natriuretic peptide increased
Cardiac failure congestive
Conjunctival hyperaemia (congestion of conjunctival vessels)
Erythema multiforme (a type of hypersensitivity reaction)
Inflammation
White blood cell count increased

What are the common drug interactions of Voltaren and Claforan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Atrioventricular block (heart block)
Bacterial infection
Blood pressure decreased
Heart rate decreased
Malaise (a feeling of general discomfort or uneasiness)
Proteinuria (presence of protein in the urine)
Pyrexia (fever)
Sick sinus syndrome (a collection of heart rhythm disorders)
Blood lactate dehydrogenase increased
Brain natriuretic peptide increased

20-29:

n/a

30-39:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Dyspnoea (difficult or laboured respiration)
Haemophilus infection (bacterial infection by haemophilus influenzae)
Headache (pain in head)
Infection
Influenza like illness
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Sore throat (pain or irritation of the throat)
Tooth abscess (pus formation in tooth)

40-49:

Alanine aminotransferase increased
Blood lactate dehydrogenase increased
C-reactive protein increased
Enanthema (rash formed inside the body)
Erythema (redness of the skin)
Gamma-glutamyltransferase increased
Oral mucosal erythema (redness of the mucous membrane of mouth)
Pruritus (severe itching of the skin)
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

Cerebral infarction (less blood supply to brain resulting tissue damage)
Nephrogenic diabetes insipidus (a disorder in which a defect in the small tubes (tubules) in the kidneys causes a person to pass a large amount of urine)

60+:

Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Hyperkalaemia (damage to or disease of the kidney)
Inflammation
Rash pruritic (redness with itching)
Renal failure acute (rapid kidney dysfunction)
Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Acute respiratory failure
Blood urea increased
Breath sounds

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 35.29%
Fever: 5 people, 29.41%
Bacterial Infection: 3 people, 17.65%
Sedation: 3 people, 17.65%
Upper Respiratory Tract Inflammation: 3 people, 17.65%
Brain Abscess: 2 people, 11.76%
Urinary Tract Infection: 2 people, 11.76%
Intervertebral Discitis (infection in the intervertebral disc space): 2 people, 11.76%
Pyogenic Liver Abscess (liver abscess caused by bacteria): 2 people, 11.76%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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