Voltaren and Gleevec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Gleevec (imatinib mesylate). Common drug interactions include eye disorder among females and haematocrit decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Gleevec. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

47 people who take Voltaren and Gleevec together, and have interactions are studied.

What are the common drug interactions of Voltaren and Gleevec, by gender? *:

female:

Eye disorder
Haematuria (presence of blood in urine)
Joint swelling
Local swelling (swelling at the site of some application of substance or injury)
Muscle spasms (muscle contraction)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Oedema (fluid collection in tissue)
Alanine aminotransferase increased
Aspartate aminotransferase increased

male:

Haematocrit decreased
Haemoglobin decreased
Scrotal swelling
Septic shock (shock due to blood infection)
Erythema (redness of the skin)
Gangrene (body tissue dies)
Hypotension (abnormally low blood pressure)
Sepsis (a severe blood infection that can lead to organ failure and death)
Arthralgia (joint pain)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Voltaren and Gleevec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Face oedema (swelling of face)
Hepatic failure (liver failure)
Muscle cramps (painful sensations caused by muscle contraction)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Platelet count decreased
Pyrexia (fever)
Thrombocytopenia (decrease of platelets in blood)
White blood cell count decreased

40-49:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase nos increased
Blood bilirubin increased
Hepatic function abnormal
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Rash
Rigors (an episode of shaking or exaggerated shivering)
Blood lactate dehydrogenase increased

50-59:

Septic shock (shock due to blood infection)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Crepitations (noises are produced by the rubbing of parts one against the other)
Erythema (redness of the skin)
Face oedema (swelling of face)
Gangrene (body tissue dies)
Hypotension (abnormally low blood pressure)
Incisional drainage
Nausea (feeling of having an urge to vomit)
Proctalgia (pain in the rectum)

60+:

Haematocrit decreased
Haemoglobin decreased
Melaena (the passage of black, tarry stools)
Nasopharyngitis (inflammation of the nasopharynx)
Pain in extremity
Vision blurred
Blood alkaline phosphatase increased
Blood bilirubin increased
Blood creatinine increased
Blood lactate dehydrogenase increased

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 14 people, 29.79%
Gastrointestinal Stromal Tumor: 13 people, 27.66%
Spinal Cord Injury Thoracic (spinal cord injury at thoracic vertebrae region): 6 people, 12.77%
Diabetes: 6 people, 12.77%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

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