Voltaren and Glucovance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Glucovance (glyburide; metformin hydrochloride). Common drug interactions include cognitive disorder among females and drug effect decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Glucovance. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Glucovance?

Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.

On Aug, 11, 2026

28 people who take Voltaren and Glucovance together, and have interactions are studied.

Voltaren and Glucovance drug interactions.

What are the common drug interactions of Voltaren and Glucovance, by gender? *:

female:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Diplopia (double vision)
Dysarthria (speech disorder)
Facial bones fracture (bone fracture of face)
Fall
Fatigue (feeling of tiredness)
Gait disturbance
Glycosylated haemoglobin increased
Hemiparesis (weakness on one side of the body)
Incontinence (lack of moderation or self-control)

male:

Drug effect decreased
Medullary thyroid cancer (type of thyroid cancer that develops in the parafollicular cells of the thyroid gland)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

What are the common drug interactions of Voltaren and Glucovance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Asthenia (weakness)
Balance disorder
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Diplopia (double vision)
Dysarthria (speech disorder)
Facial bones fracture (bone fracture of face)
Fall
Fatigue (feeling of tiredness)

60+:

Interstitial lung disease
Glycosylated haemoglobin increased
Nephrogenic anaemia (anaemia due to kidney disease)
Pulmonary haemorrhage (acute bleeding from the lung)
Renal failure (kidney dysfunction)
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
Vasculitis (inflammation of a blood vessel or blood vessels)
Blood glucose increased
Gangrene (body tissue dies)
Muscle abscess (pus in muscle)

What are the existing conditions these people have? *

Type 2 Diabetes: 16 people, 57.14%
Stress And Anxiety: 5 people, 17.86%
Constipation: 4 people, 14.29%
Insomnia (sleeplessness): 3 people, 10.71%
Cellulitis (infection under the skin): 3 people, 10.71%
Depression: 3 people, 10.71%
Dizziness: 3 people, 10.71%
Headache (pain in head): 3 people, 10.71%
High Blood Pressure: 3 people, 10.71%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 10.71%

* Approximation only. Some reports may have incomplete information.

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