Voltaren and Pentazocine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Pentazocine (pentazocine hydrochloride). Common drug interactions include chronic kidney disease among females and blood cholesterol increased among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Pentazocine. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Pentazocine?

Pentazocine has active ingredients of pentazocine hydrochloride. eHealthMe is studying from 741 Pentazocine users. Check the latest studies of Pentazocine.



On Jul, 27, 2026

14 people who take Voltaren and Pentazocine together, and have interactions are studied.

Voltaren and Pentazocine drug interactions.

What are the common drug interactions of Voltaren and Pentazocine, by gender? *:

female:

  1. Chronic kidney disease
  2. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  3. Urinary tract infection
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Renal failure (kidney dysfunction)
  6. Vascular pseudoaneurysm (leakage of arterial blood from an artery into the surrounding tissue with a continuing communication between the originating artery and the resultant adjacent cavity)

male:

  1. Blood cholesterol increased
  2. Cataract (clouding of the lens inside the eye)
  3. Insomnia (sleeplessness)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Nausea (feeling of having an urge to vomit)
  6. Normal tension glaucoma (a unique condition in which optic nerve damage and vision loss have occurred despite a normal pressure inside the eye)
  7. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  8. Priapism (prolonged and painful erection that can last from several hours up to a few days)
  9. Thirst
  10. Libido decreased (loss of interest in sex)

What are the common drug interactions of Voltaren and Pentazocine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Anoxia (low oxygen)
  2. Apnoea (suspension of external breathing)
  3. Depressed level of consciousness
  4. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  5. Respiratory disorder (respiratory disease)
  6. Chronic kidney disease
  7. Fall
  8. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  9. Hypotension (abnormally low blood pressure)
  10. Inflammation

60+:

  1. Blood cholesterol increased
  2. Cataract (clouding of the lens inside the eye)
  3. Insomnia (sleeplessness)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Nausea (feeling of having an urge to vomit)
  6. Normal tension glaucoma (a unique condition in which optic nerve damage and vision loss have occurred despite a normal pressure inside the eye)
  7. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  8. Priapism (prolonged and painful erection that can last from several hours up to a few days)
  9. Thirst
  10. Libido decreased (loss of interest in sex)

What are the existing conditions these people have? *

  1. Pain: 9 people, 64.29%
  2. Depression: 7 people, 50.00%
  3. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 6 people, 42.86%
  4. Constipation: 2 people, 14.29%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
  6. Thrombotic Cerebral Infarction (death of cerebral tissue due to clot formation): 1 person, 7.14%
  7. Hypersensitivity: 1 person, 7.14%
  8. Colon Cancer: 1 person, 7.14%
  9. Facial Paralysis (loss of function of face muscle): 1 person, 7.14%
  10. Gastric Ulcer (stomach ulcer): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Voltaren and Pentazocine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Voltaren and Pentazocine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Voltaren:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pentazocine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Voltaren and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pentazocine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium and pentazocine hydrochloride (the active ingredients of Voltaren and Pentazocine, respectively), and Voltaren and Pentazocine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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