Voltaren and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Soliris (eculizumab). Common drug interactions include sinusitis among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Soliris. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.



On Aug, 09, 2026

71 people who take Voltaren and Soliris together, and have interactions are studied.

Voltaren and Soliris drug interactions.

What are the common drug interactions of Voltaren and Soliris, by gender? *:

female:

  1. Sinusitis (inflammation of sinus)
  2. Stress
  3. Ventricle rupture (heart rupture)
  4. Abdominal distension
  5. Bone pain
  6. Dermatitis herpetiformis (chronic blistering skin condition, characterized by blisters filled with a watery fluid)
  7. Diplopia (double vision)
  8. Drug ineffective
  9. Dysphagia (a condition in which swallowing is difficult or painful)
  10. Dysphonia (speech disorder attributable to a disorder of phonation)

male:

  1. Asthenia (weakness)
  2. Haemoglobin decreased
  3. Pain in extremity
  4. Pyrexia (fever)
  5. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
  6. Headache (pain in head)
  7. Hypoxia (low oxygen in tissues)
  8. Night sweats (sweating in night)
  9. Parainfluenzae virus infection
  10. Pneumonia

What are the common drug interactions of Voltaren and Soliris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Haemoglobin decreased
  2. Sinusitis (inflammation of sinus)

40-49:

  1. Pain in extremity
  2. Peripheral swelling
  3. Arteriovenous fistula occlusion
  4. Cough
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Oropharyngeal pain
  7. Rhinorrhoea (watery mucus discharge from the nose)
  8. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  9. Thrombosis (formation of a blood clot inside a blood vessel)
  10. Productive cough

50-59:

  1. Abscess (pus)
  2. Chills (felling of cold)
  3. Furuncle (infection of the hair follicle)
  4. Herpes zoster
  5. Pain in extremity
  6. Pyrexia (fever)
  7. Skin fibrosis (fibrous tissue formation on skin)
  8. Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
  9. Dehydration (dryness resulting from the removal of water)
  10. Haemoglobin decreased

60+:

  1. Haemoglobin decreased
  2. Blood magnesium decreased
  3. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  4. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  5. Pain in extremity
  6. Pyrexia (fever)
  7. Road traffic accident
  8. Tooth abscess (pus formation in tooth)
  9. Tooth infection
  10. Abdominal pain

What are the existing conditions these people have? *

  1. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 36 people, 50.70%
  2. High Blood Pressure: 35 people, 49.30%
  3. Diabetes: 19 people, 26.76%
  4. Pain: 18 people, 25.35%
  5. Tendonitis (a condition that causes pain and swelling of tendons): 15 people, 21.13%
  6. Anaemia (lack of blood): 12 people, 16.90%
  7. Pain In Extremity: 11 people, 15.49%
  8. Ocular Hyperaemia (an abnormally large amount of blood in eye): 6 people, 8.45%
  9. Headache (pain in head): 6 people, 8.45%
  10. Meningitis Bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 5 people, 7.04%

* Approximation only. Some reports may have incomplete information.

Do you take Voltaren and Soliris?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Voltaren and Soliris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Voltaren:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Soliris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Voltaren and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Soliris and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium and eculizumab (the active ingredients of Voltaren and Soliris, respectively), and Voltaren and Soliris (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: