Voltaren and Tapazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Tapazole (methimazole). Common drug interactions include abdominal pain upper among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Tapazole. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Tapazole?

Tapazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 2,477 Tapazole users. Check the latest studies of Tapazole.



On Jul, 21, 2026

15 people who take Voltaren and Tapazole together, and have interactions are studied.

Voltaren and Tapazole drug interactions.

What are the common drug interactions of Voltaren and Tapazole, by gender? *:

female:

  1. Abdominal pain upper
  2. Constipation
  3. Diarrhoea
  4. Vomiting
  5. Arthralgia (joint pain)
  6. C-reactive protein increased
  7. Asthenia (weakness)
  8. Back pain
  9. Bone pain
  10. Chest pain

male:

  1. Anaemia (lack of blood)
  2. Back pain
  3. Dysplasia (enlargement of an organ or tissue)
  4. Haematocrit decreased
  5. Haemoglobin decreased
  6. Hyperbilirubinaemia (excess of bilirubin in the blood)
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Light chain analysis increased
  9. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  10. Mean cell haemoglobin decreased (less than normal haemoglobin per red blood cell in a sample of blood)

What are the common drug interactions of Voltaren and Tapazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Back pain
  3. Bone pain
  4. Chest pain
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Cough
  7. Discomfort
  8. Fatigue (feeling of tiredness)
  9. Influenza
  10. Insomnia (sleeplessness)

50-59:

  1. Abdominal pain upper
  2. Constipation
  3. Diarrhoea
  4. Vomiting
  5. C-reactive protein increased
  6. Arthralgia (joint pain)
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Dizziness
  10. Nasopharyngitis (inflammation of the nasopharynx)

60+:

  1. Anaemia (lack of blood)
  2. Asthenia (weakness)
  3. Blood urea increased
  4. Carbon dioxide decreased
  5. Cardioactive drug level decreased
  6. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  7. Dysplasia (enlargement of an organ or tissue)
  8. Dyspnoea exertional (breathlessness or shortness of breath)
  9. Faeces discoloured
  10. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 8 people, 53.33%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 13.33%
  3. Thyroid Mass: 1 person, 6.67%
  4. Muscle Aches (muscle pain): 1 person, 6.67%
  5. Joint Pain: 1 person, 6.67%
  6. Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 1 person, 6.67%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.67%
  8. Arrhythmias (irregular heartbeat): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Voltaren and Tapazole?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Voltaren and Tapazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Voltaren:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tapazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Voltaren and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tapazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium and methimazole (the active ingredients of Voltaren and Tapazole, respectively), and Voltaren and Tapazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: