Voltaren and Timoptic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Timoptic (timolol maleate). Common drug interactions include heart rate increased among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Timoptic. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Timoptic?

Timoptic has active ingredients of timolol maleate. It is often used in glaucoma. eHealthMe is studying from 4,247 Timoptic users. Check the latest studies of Timoptic.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

32 people who take Voltaren and Timoptic together, and have interactions are studied.

Voltaren and Timoptic drug interactions.

What are the common drug interactions of Voltaren and Timoptic, by gender? *:

female:

Heart rate increased
High density lipoprotein decreased
Hyperhidrosis (abnormally increased sweating)
Impaired healing
Inflammation
Intervertebral disc degeneration (spinal disc degeneration)
Lymphoedema (localized fluid retention and tissue swelling)
Mania (a state of abnormally elevated or irritable mood)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Mitral valve incompetence (inefficient heart valve)

male:

Decreased appetite
Diarrhoea
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug ineffective
Drug toxicity
Iritis (painful inflammation of the iris of the eye)
Lymphostasis (obstruction of the normal flow of lymph)
Pericardial effusion (fluid around the heart)
Pleural fibrosis (formation of fibrous tissue in lung)
Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Voltaren and Timoptic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
Cataract (clouding of the lens inside the eye)
Reaction to drug excipients
Thrombocytopenia (decrease of platelets in blood)

60+:

Diarrhoea
Decreased appetite
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood cholesterol increased
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cellulitis (infection under the skin)
Confusional state

What are the existing conditions these people have? *

Prostate Cancer: 4 people, 12.50%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 3 people, 9.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.25%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 6.25%
Hyperkalemia (damage to or disease of the kidney): 2 people, 6.25%
High Blood Pressure: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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