Voltaren and Truvada drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Truvada (emtricitabine; tenofovir disoproxil fumarate). Common drug interactions include amylase increased among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Truvada. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.

On Jul, 16, 2026

78 people who take Voltaren and Truvada together, and have interactions are studied.

What are the common drug interactions of Voltaren and Truvada, by gender? *:

female:

Amylase increased
Cholangitis (infection of the bile duct)
Hepatic enzyme increased
Pancreatitis acute (sudden inflammation of pancreas)
Cachexia (loss of weight)
Cd4 lymphocytes decreased
Infection
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Renal impairment (severely reduced kidney function)

male:

Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Hyperaesthesia
Fatigue (feeling of tiredness)
Foot fracture
Mobility decreased (ability to move is reduced)
Drug abuse
Asthenia (weakness)
Hyperphosphaturia (excess of phosphates in the urine)
Osteonecrosis (death of bone)

What are the common drug interactions of Voltaren and Truvada, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cellulitis (infection under the skin)
Erythema (redness of the skin)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Injury
Lymphoedema (localized fluid retention and tissue swelling)
Pain in extremity
Premature baby
Respiratory distress (difficulty in breathing)
Tenderness (pain or discomfort when an affected area is touched)

20-29:

Cachexia (loss of weight)
Cd4 lymphocytes decreased
Infection
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Urine output decreased

30-39:

Disease recurrence
Abasia (inability to walk)
Anal cancer
Asthenia (weakness)
Bone density decreased
Chest pain
Depressed mood
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Erectile dysfunction
Fatigue (feeling of tiredness)

40-49:

Memory impairment
Nasopharyngitis (inflammation of the nasopharynx)
Pneumonia
Decreased activity
Depression
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Osteonecrosis (death of bone)
Panic attack
Quality of life decreased

50-59:

Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Bone density decreased
Multiple fractures
Allodynia (a condition in which pain is caused by a stimulus that does not normally elicit pain)
Hyperaesthesia
Mobility decreased (ability to move is reduced)
Osteoporosis (bones weak and more likely to break)

60+:

Osteoporosis (bones weak and more likely to break)
Emotional distress
Foot fracture
Hip fracture
Multiple fractures
Tooth loss
Arthropathy
Gait disturbance
Hepatic steatosis (fatty liver disease)
Chronic kidney disease

What are the existing conditions these people have? *

Pain: 13 people, 16.67%
High Blood Pressure: 9 people, 11.54%
Osteoporosis (bones weak and more likely to break): 7 people, 8.97%
Depression: 7 people, 8.97%
Stress And Anxiety: 6 people, 7.69%
Hypersensitivity: 6 people, 7.69%
Joint Pain: 5 people, 6.41%
High Blood Cholesterol: 5 people, 6.41%
Bipolar Disorder (mood disorder): 5 people, 6.41%
Nausea (feeling of having an urge to vomit): 4 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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