Vortioxetine and Naltrexone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vortioxetine (vortioxetine) and Naltrexone (naltrexone). Common drug interactions include myoglobinuria among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Vortioxetine and Naltrexone. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Vortioxetine?

Vortioxetine has active ingredients of vortioxetine. eHealthMe is studying from 2,440 Vortioxetine users. Check the latest studies of Vortioxetine.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,835 Naltrexone users. Check the latest studies of Naltrexone.

On Aug, 11, 2026

23 people who take Vortioxetine and Naltrexone together, and have interactions are studied.

Vortioxetine and Naltrexone drug interactions.

What are the common drug interactions of Vortioxetine and Naltrexone, by gender? *:

female:

Myoglobinuria (presence of myoglobin in the urine)
Myopathy (a muscular disease in which the muscle fibres do not function)
Renal failure (kidney dysfunction)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Body temperature increased
Chills (felling of cold)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Apathy
Bipolar disorder (mood disorder)
Chronic kidney disease
Depressed mood
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Psychiatric symptom
Renal failure (kidney dysfunction)
Sedation

What are the common drug interactions of Vortioxetine and Naltrexone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Myoglobinuria (presence of myoglobin in the urine)
Myopathy (a muscular disease in which the muscle fibres do not function)
Renal failure (kidney dysfunction)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Body temperature increased
Chills (felling of cold)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)

30-39:

Anaphylactic reaction (serious allergic reaction)
Hypersensitivity
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Throat irritation

40-49:

n/a

50-59:

n/a

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Apathy
Bipolar disorder (mood disorder)
Chronic kidney disease
Depressed mood
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Psychiatric symptom
Renal failure (kidney dysfunction)
Sedation

What are the existing conditions these people have? *

Weight Loss: 19 people, 82.61%
Nausea (feeling of having an urge to vomit): 10 people, 43.48%

* Approximation only. Some reports may have incomplete information.

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