Votrient and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Votrient (pazopanib hydrochloride) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include abdominal discomfort among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Votrient and Valacyclovir. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Votrient?

Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 25,347 Votrient users. Check the latest studies of Votrient.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 18, 2026

15 people who take Votrient and Valacyclovir together, and have interactions are studied.

Votrient and Valacyclovir drug interactions.

What are the common drug interactions of Votrient and Valacyclovir, by gender? *:

female:

Abdominal discomfort
Diarrhoea
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Asthenia (weakness)
Constipation
Dyspepsia (indigestion)
Eating disorder
Pain
Death

male:

Diarrhoea
Abdominal distension
Platelet count decreased
Red cell distribution width increased
Weight decreased
Nausea (feeling of having an urge to vomit)
Death
Malignant neoplasm progression (cancer tumour came back)
Skin disorder (skin disease)
Alanine aminotransferase increased

What are the common drug interactions of Votrient and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Malignant neoplasm progression (cancer tumour came back)
Nausea (feeling of having an urge to vomit)
Skin disorder (skin disease)
Death

50-59:

Diarrhoea
Weight decreased
Abdominal distension
Adverse drug reaction
Flatulence (flatus expelled through the anus)
Gamma-glutamyltransferase increased
Headache (pain in head)
Hepatic enzyme increased
Intestinal haemorrhage (bleeding from intestine)
Intestinal perforation (complete penetration of the wall of the intestine)

60+:

Abdominal discomfort
Death
Nausea (feeling of having an urge to vomit)
Pain
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Dehydration (dryness resulting from the removal of water)
Vomiting
Abdominal pain upper
Alanine aminotransferase increased

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 8 people, 53.33%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 3 people, 20.00%
Neoplasm Malignant (cancer tumour): 2 people, 13.33%
Prostate Cancer: 1 person, 6.67%
Pain: 1 person, 6.67%
Multiple Myeloma (cancer of the plasma cells): 1 person, 6.67%
Malignant Soft Tissue Neoplasm (cancer tumour of soft tissue): 1 person, 6.67%
Leiomyosarcoma (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue): 1 person, 6.67%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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