Vraylar and Memantine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vraylar (cariprazine hydrochloride) and Memantine (memantine). Common drug interactions include drug ineffective among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Vraylar and Memantine. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Vraylar?

Vraylar has active ingredients of cariprazine hydrochloride. eHealthMe is studying from 6,136 Vraylar users. Check the latest studies of Vraylar.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.



On Aug, 04, 2026

12 people who take Vraylar and Memantine together, and have interactions are studied.

Vraylar and Memantine drug interactions.

What are the common drug interactions of Vraylar and Memantine, by gender? *:

female:

  1. Drug ineffective
  2. Latent tuberculosis (hidden tuberculosis)
  3. Suicidal ideation

male:

  1. Confusional state
  2. Anxiety
  3. Dehydration (dryness resulting from the removal of water)
  4. Hypoaldosteronism (decreased levels of the hormone aldosterone)
  5. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  6. Renal failure (kidney dysfunction)
  7. Somnambulism (sleep walking)
  8. Angiopathy (generic term for a disease of the blood vessels)
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

What are the common drug interactions of Vraylar and Memantine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Angiopathy (generic term for a disease of the blood vessels)
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Chest pain
  6. Depression
  7. Disturbance in attention
  8. Dyspnoea (difficult or laboured respiration)
  9. Fatigue (feeling of tiredness)
  10. Hypersensitivity

30-39:

n/a

40-49:

  1. Anxiety
  2. Aspartate aminotransferase increased
  3. Essential hypertension (primary hypertension)
  4. Hypertension (high blood pressure)
  5. Confusional state
  6. Disturbance in attention
  7. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Hypermetabolism (abnormal increase in the body's basal metabolic rate)
  10. Night sweats (sweating in night)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 58.33%
  2. Psoriasis (immune-mediated disease that affects the skin): 2 people, 16.67%
  3. Constipation: 1 person, 8.33%
  4. Breast Cancer Female: 1 person, 8.33%
  5. Bipolar Disorder (mood disorder): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vraylar and Memantine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vraylar and Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vraylar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vraylar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Memantine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cariprazine hydrochloride and memantine (the active ingredients of Vraylar and Memantine, respectively), and Vraylar and Memantine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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