Vraylar and Zolpidem drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vraylar (cariprazine hydrochloride) and Zolpidem (zolpidem tartrate). Common drug interactions include staphylococcal sepsis among females and headache among males.
The phase IV clinical study analyzes what interactions people have when they take Vraylar and Zolpidem. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.
What is Vraylar?
Vraylar has active ingredients of cariprazine hydrochloride. eHealthMe is studying from 6,136 Vraylar users. Check the latest studies of Vraylar.
What is Zolpidem?
Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.
64 people who take Vraylar and Zolpidem together, and have interactions are studied.

What are the common drug interactions of Vraylar and Zolpidem, by gender? *:
female:
- Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
- Stress
- Suicidal ideation
- Tardive dyskinesia (a disorder that involves involuntary movements)
- Tongue disorder (disease of tongue)
- Vitamin d decreased
- Tremor (trembling or shaking movements in one or more parts of your body)
- Hospitalisation
- Anxiety
- Bipolar disorder (mood disorder)
male:
- Headache (pain in head)
- Head injury
- Physical assault
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Spinal disorder (disease of spine a back bone)
- Suicidal ideation
- Diarrhoea
- Jaw fracture
- Abdominal pain upper
- Arrhythmia (irregular heartbeat)
What are the common drug interactions of Vraylar and Zolpidem, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Migraine (headache)
- Diarrhoea
- Road traffic accident
40-49:
- Alopecia (absence of hair from areas of the body)
- Cough
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
- Pyrexia (fever)
- Asthma
- Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
- Blood cholesterol increased
- Blood pressure increased
- Chronic kidney disease
- Concussion (short loss of normal brain function in response to a head injury)
50-59:
- Head injury
- Brain injury
- Concussion (short loss of normal brain function in response to a head injury)
- Contusion (a type of hematoma of tissue in which capillaries)
- Dry mouth
- Fall
- Headache (pain in head)
- Injury
- Joint injury
- Physical assault
60+:
- Fall
- Asthenia (weakness)
- Balance disorder
- Agitation (state of anxiety or nervous excitement)
- Diarrhoea
- Hypertension (high blood pressure)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Fatigue (feeling of tiredness)
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Anxiety
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 17.19%
- Pain: 9 people, 14.06%
- Hereditary Angioedema (recurrent episodes of severe swelling): 9 people, 14.06%
- Depression: 5 people, 7.81%
* Approximation only. Some reports may have incomplete information.
Do you take Vraylar and Zolpidem?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vraylar and Zolpidem:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vraylar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zolpidem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vraylar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zolpidem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cariprazine hydrochloride and zolpidem tartrate (the active ingredients of Vraylar and Zolpidem, respectively), and Vraylar and Zolpidem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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