Vyepti and Klonopin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vyepti (eptinezumab-jjmr) and Klonopin (clonazepam). Common drug interactions include bronchitis among females and anaphylactic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Vyepti and Klonopin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Vyepti?

Vyepti has active ingredients of eptinezumab-jjmr. eHealthMe is studying from 4,897 Vyepti users. Check the latest studies of Vyepti.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.



On Jul, 08, 2026

15 people who take Vyepti and Klonopin together, and have interactions are studied.

Vyepti and Klonopin drug interactions.

What are the common drug interactions of Vyepti and Klonopin, by gender? *:

female:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Cardiac valve disease (heart valve disease)
  3. Chest discomfort
  4. Chills (felling of cold)
  5. Clavicle fracture
  6. Dyspnoea (difficult or laboured respiration)
  7. Erythema (redness of the skin)
  8. Head injury
  9. Infusion related reaction
  10. Limb discomfort (discomfort in leg)

male:

  1. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  2. Headache (pain in head)
  3. Infusion related reaction
  4. Rash
  5. Throat tightness

What are the common drug interactions of Vyepti and Klonopin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  2. Drug ineffective
  3. Headache (pain in head)
  4. Infusion related reaction
  5. Rash
  6. Throat tightness

30-39:

  1. Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop)

40-49:

  1. Hypersensitivity
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Balance disorder
  4. Clumsiness (a lack of coordination or elegance)
  5. Diplopia (double vision)
  6. Dysarthria (speech disorder)
  7. Fall
  8. Feeling drunk
  9. Headache (pain in head)
  10. Ligament sprain (ligament stretched)

50-59:

  1. Hallucination (an experience involving the perception of something not present)
  2. Migraine (headache)
  3. Suicidal ideation
  4. Suicide attempt
  5. Dizziness
  6. Fatigue (feeling of tiredness)
  7. Heart rate increased
  8. Nausea (feeling of having an urge to vomit)
  9. Drug ineffective
  10. Hospitalisation

60+:

  1. Migraine (headache)
  2. Blood pressure decreased
  3. Fatigue (feeling of tiredness)
  4. Head injury
  5. Infusion related reaction
  6. Limb discomfort (discomfort in leg)
  7. Memory impairment
  8. Pneumonia
  9. Productive cough
  10. Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

  1. Migraine (headache): 10 people, 66.67%
  2. Immunodeficiency Common Variable: 4 people, 26.67%
  3. Headache (pain in head): 2 people, 13.33%
  4. Secondary Immunodeficiency (lack of immunity due to some disease): 1 person, 6.67%
  5. Primary Immunodeficiency Syndrome: 1 person, 6.67%
  6. Migraine Without Aura (headache without neurological problems): 1 person, 6.67%
  7. Immunodeficiency: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vyepti and Klonopin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vyepti:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Klonopin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vyepti and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Klonopin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on eptinezumab-jjmr and clonazepam (the active ingredients of Vyepti and Klonopin, respectively), and Vyepti and Klonopin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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