Vyepti and Sumatriptan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vyepti (eptinezumab-jjmr) and Sumatriptan (sumatriptan succinate). Common drug interactions include drug ineffective among females and paraesthesia among males.

The phase IV clinical study analyzes what interactions people have when they take Vyepti and Sumatriptan. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Vyepti?

Vyepti has active ingredients of eptinezumab-jjmr. eHealthMe is studying from 4,897 Vyepti users. Check the latest studies of Vyepti.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

On Jul, 19, 2026

69 people who take Vyepti and Sumatriptan together, and have interactions are studied.

Vyepti and Sumatriptan drug interactions.

What are the common drug interactions of Vyepti and Sumatriptan, by gender? *:

female:

Drug ineffective
Headache (pain in head)
Constipation
Fatigue (feeling of tiredness)
Oropharyngeal pain
Nausea (feeling of having an urge to vomit)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Throat irritation
Disturbance in attention
Sinusitis (inflammation of sinus)

male:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Asthenia (weakness)
Change of bowel habit
Drug ineffective
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Visual impairment
Dysgeusia (disorder of the sense of taste)
Erectile dysfunction
Libido decreased (loss of interest in sex)
Nasopharyngitis (inflammation of the nasopharynx)

What are the common drug interactions of Vyepti and Sumatriptan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Vomiting

20-29:

Drug ineffective
Infusion site rash
Nausea (feeling of having an urge to vomit)

30-39:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Throat irritation
Headache (pain in head)
Disturbance in attention
Constipation
Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Oropharyngeal pain
Aura
Confusional state

40-49:

Throat irritation
Fatigue (feeling of tiredness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Oropharyngeal pain
Blood pressure increased
Drug ineffective
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Urticaria (rash of round, red welts on the skin that itch intensely)
Cough

50-59:

Drug ineffective
Oropharyngeal pain
Headache (pain in head)
Fatigue (feeling of tiredness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Hypersensitivity
Sneezing
Visual impairment
Anxiety

60+:

Headache (pain in head)
Dizziness
Dyspnoea (difficult or laboured respiration)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Speech disorder
Alopecia (absence of hair from areas of the body)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dry eye (lack of adequate tears)
Dry skin
Increased appetite

What are the existing conditions these people have? *

Headache (pain in head): 6 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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