Vyvanse and Clozaril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vyvanse (lisdexamfetamine dimesylate) and Clozaril (clozapine). Common drug interactions include adverse reaction among females and weight increased among males.

The phase IV clinical study analyzes what interactions people have when they take Vyvanse and Clozaril. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Vyvanse?

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 35,868 Vyvanse users. Check the latest studies of Vyvanse.

What is Clozaril?

Clozaril has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 65,127 Clozaril users. Check the latest studies of Clozaril.

On Jul, 21, 2026

11 people who take Vyvanse and Clozaril together, and have interactions are studied.

What are the common drug interactions of Vyvanse and Clozaril, by gender? *:

female:

Adverse reaction
Depressed mood
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Panic reaction
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)

male:

Weight increased
Eating disorder
Negative thoughts
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Sleep disorder
Tardive dyskinesia (a disorder that involves involuntary movements)
White blood cell count increased
Psychotic disorder

What are the common drug interactions of Vyvanse and Clozaril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Weight increased
White blood cell count increased
Psychotic disorder
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Lipids increased (excess lipid in body)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)

20-29:

Aggression
Eating disorder
Hallucination (an experience involving the perception of something not present)
Sleep disorder
Weight increased

30-39:

Adverse reaction

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 27.27%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 18.18%
Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 2 people, 18.18%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 18.18%
Mood Swings (an extreme or rapid change in mood): 2 people, 18.18%
Depression: 2 people, 18.18%
Tardive Dyskinesia (a disorder that involves involuntary movements): 1 person, 9.09%
Psychotic Disorder: 1 person, 9.09%
Metabolic Syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease): 1 person, 9.09%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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