Vyvanse and Diamox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vyvanse (lisdexamfetamine dimesylate) and Diamox (acetazolamide). Common drug interactions include acne among females and mountain sickness acute among males.

The phase IV clinical study analyzes what interactions people have when they take Vyvanse and Diamox. It is created by eHealthMe based on reports of 10 people who take the same drugs from the FDA, and is updated regularly.

What is Vyvanse?

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 35,870 Vyvanse users. Check the latest studies of Vyvanse.

What is Diamox?

Diamox has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,711 Diamox users. Check the latest studies of Diamox.

On Jun, 10, 2026

10 people who take Vyvanse and Diamox together, and have interactions are studied.

What are the common drug interactions of Vyvanse and Diamox, by gender? *:

female:

Acne (skin problems that cause pimples)
Aphthous ulcer (mouth ulcer)
Cataract (clouding of the lens inside the eye)
Dry eye (lack of adequate tears)
Encephalitis (inflammation of the brain)
Eye disorder
Heart rate increased
Joint swelling
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Oral pain

male:

Mountain sickness acute (a reaction to the lower amounts of oxygen available at high altitudes (due to the lower air pressure))
Pulmonary oedema (fluid accumulation in the lungs)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Nausea (feeling of having an urge to vomit)
Weight decreased

What are the common drug interactions of Vyvanse and Diamox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Encephalitis (inflammation of the brain)
Eye disorder
Heart rate increased
Joint swelling
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Mouth ulceration (mouth ulcers)
Oral pain
Uveitis (inflammation of the uvea)
Abdominal discomfort
Acne (skin problems that cause pimples)

30-39:

n/a

40-49:

Mountain sickness acute (a reaction to the lower amounts of oxygen available at high altitudes (due to the lower air pressure))
Pulmonary oedema (fluid accumulation in the lungs)

50-59:

Blood glucose increased

60+:

n/a

What are the existing conditions these people have? *

Uveitis (inflammation of the uvea): 6 people, 60.00%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 6 people, 60.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 10.00%
Drowsiness: 1 person, 10.00%
Diabetes: 1 person, 10.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

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