Vyvanse and Spiriva respimat drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vyvanse (lisdexamfetamine dimesylate) and Spiriva respimat (tiotropium bromide). Common drug interactions include dyspnoea among females and anaphylactic reaction among males.
The phase IV clinical study analyzes what interactions people have when they take Vyvanse and Spiriva respimat. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Vyvanse?
Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 35,868 Vyvanse users. Check the latest studies of Vyvanse.
What is Spiriva respimat?
Spiriva respimat has active ingredients of tiotropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 9,788 Spiriva respimat users. Check the latest studies of Spiriva respimat.
15 people who take Vyvanse and Spiriva respimat together, and have interactions are studied.

What are the common drug interactions of Vyvanse and Spiriva Respimat, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Constipation
- Blood immunoglobulin g increased
- Ear infection
- Influenza
- Oropharyngeal pain
- Pharyngeal mass
- Pneumonia
- Pyrexia (fever)
- Respiratory tract infection
male:
- Anaphylactic reaction (serious allergic reaction)
- Hypotension (abnormally low blood pressure)
- Wheezing (a high-pitched whistling sound made while you breath)
- Anaemia (lack of blood)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Carotid artery occlusion (artery blockage)
- Cerebral haemorrhage (bleeding within the brain)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
What are the common drug interactions of Vyvanse and Spiriva Respimat, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Blood immunoglobulin g increased
- Constipation
- Dyspnoea (difficult or laboured respiration)
- Ear infection
- Influenza
- Oropharyngeal pain
- Pharyngeal mass
- Pneumonia
- Pyrexia (fever)
- Respiratory tract infection
10-19:
- Drug ineffective
- Wheezing (a high-pitched whistling sound made while you breath)
20-29:
- Tendon rupture (tear of tendon)
- Surgery
30-39:
- Anaphylactic reaction (serious allergic reaction)
- Hypotension (abnormally low blood pressure)
- Dyspnoea (difficult or laboured respiration)
- Nausea (feeling of having an urge to vomit)
40-49:
n/a
50-59:
n/a
60+:
- Anaemia (lack of blood)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Carotid artery occlusion (artery blockage)
- Cerebral haemorrhage (bleeding within the brain)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 26.67%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 26.67%
- Asthma: 3 people, 20.00%
- Immunodeficiency: 2 people, 13.33%
- Drowsiness: 2 people, 13.33%
- Type 2 Diabetes: 1 person, 6.67%
- Sinus Disorder (disease of sinus): 1 person, 6.67%
- Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.67%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 6.67%
- Neuralgia (pain in one or more nerves): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Vyvanse and Spiriva respimat?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Vyvanse (35,868 reports)
- Spiriva respimat (9,788 reports)
Browse all drug interactions of Vyvanse and Spiriva respimat:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vyvanse:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Spiriva respimat:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vyvanse and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Spiriva respimat and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Najib J, Wimer D, Zeng J, Lam KW, Romanyak N, Paige Morgan E, Thadavila A, "Review of Lisdexamfetamine Dimesylate in Adults With Attention-Deficit/Hyperactivity Disorder", Journal of central nervous system disease, 2017 Aug .
- Maneeton N, Maneeton B, Suttajit S, Reungyos J, Srisurapanont M, Martin SD, "Exploratory meta-analysis on lisdexamfetamine versus placebo in adult ADHD", Drug design, development and therapy, 2017 Jan .
- Maneeton B, Maneeton N, Likhitsathian S, Suttajit S, Narkpongphun A, Srisurapanont M, Woottiluk P, "Comparative efficacy, acceptability, and tolerability of lisdexamfetamine in child and adolescent ADHD: a meta-analysis of randomized, controlled trials", Drug design, development and therapy, 2013 Jan .
- Najib J, Wimer D, Zeng J, Lam KW, Romanyak N, Paige Morgan E, Thadavila A, "Review of Lisdexamfetamine Dimesylate in Adults With Attention-Deficit/Hyperactivity Disorder", Journal of central nervous system disease, 2017 Aug .
- Maneeton N, Maneeton B, Suttajit S, Reungyos J, Srisurapanont M, Martin SD, "Exploratory meta-analysis on lisdexamfetamine versus placebo in adult ADHD", Drug design, development and therapy, 2017 Jan .
- Maneeton B, Maneeton N, Likhitsathian S, Suttajit S, Narkpongphun A, Srisurapanont M, Woottiluk P, "Comparative efficacy, acceptability, and tolerability of lisdexamfetamine in child and adolescent ADHD: a meta-analysis of randomized, controlled trials", Drug design, development and therapy, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on lisdexamfetamine dimesylate and tiotropium bromide (the active ingredients of Vyvanse and Spiriva respimat, respectively), and Vyvanse and Spiriva respimat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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