Vyvanse and Teriflunomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vyvanse (lisdexamfetamine dimesylate) and Teriflunomide (teriflunomide). Common drug interactions include multiple sclerosis relapse among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Vyvanse and Teriflunomide. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Vyvanse?

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 35,870 Vyvanse users. Check the latest studies of Vyvanse.

What is Teriflunomide?

Teriflunomide has active ingredients of teriflunomide. eHealthMe is studying from 5,067 Teriflunomide users. Check the latest studies of Teriflunomide.



On Aug, 09, 2026

13 people who take Vyvanse and Teriflunomide together, and have interactions are studied.

Vyvanse and Teriflunomide drug interactions.

What are the common drug interactions of Vyvanse and Teriflunomide, by gender? *:

female:

  1. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  2. Alopecia (absence of hair from areas of the body)
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Pruritus (severe itching of the skin)
  6. Visual impairment
  7. Gait disturbance
  8. Abdominal pain upper
  9. Eye pruritus (eye itching)
  10. Furuncle (infection of the hair follicle)

male:

  1. Anxiety
  2. Abdominal pain upper
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Decreased appetite
  5. Energy increased
  6. Pain in extremity
  7. Pericardial effusion (fluid around the heart)
  8. Weight decreased
  9. Anger
  10. Dizziness

What are the common drug interactions of Vyvanse and Teriflunomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

40-49:

  1. Alopecia (absence of hair from areas of the body)
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Pruritus (severe itching of the skin)
  5. Visual impairment
  6. Hypertension (high blood pressure)
  7. Abdominal pain upper
  8. Eye pruritus (eye itching)
  9. Furuncle (infection of the hair follicle)
  10. Hot flush (sudden feelings of heat)

50-59:

  1. Drug ineffective

60+:

  1. Asthenia (weakness)
  2. Feeding disorder (when children refuse to eat certain food groups)
  3. Energy increased
  4. Pain in extremity
  5. Pericardial effusion (fluid around the heart)
  6. Weight decreased
  7. Gait disturbance
  8. Gallbladder disorder
  9. Memory impairment
  10. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 76.92%
  2. Depression: 3 people, 23.08%
  3. Stress And Anxiety: 2 people, 15.38%
  4. Insomnia (sleeplessness): 2 people, 15.38%
  5. Fatigue (feeling of tiredness): 2 people, 15.38%
  6. Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 7.69%
  7. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.69%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.69%
  10. High Blood Pressure: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vyvanse and Teriflunomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vyvanse:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Teriflunomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vyvanse and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Teriflunomide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lisdexamfetamine dimesylate and teriflunomide (the active ingredients of Vyvanse and Teriflunomide, respectively), and Vyvanse and Teriflunomide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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