Warfarin sodium and Arthrotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Warfarin sodium (warfarin sodium) and Arthrotec (diclofenac sodium; misoprostol). Common drug interactions include asthma among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Warfarin sodium and Arthrotec. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Warfarin sodium?

Warfarin sodium has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 71,174 Warfarin sodium users. Check the latest studies of Warfarin sodium.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.

On Jul, 06, 2026

60 people who take Warfarin sodium and Arthrotec together, and have interactions are studied.

Warfarin sodium and Arthrotec drug interactions.

What are the common drug interactions of Warfarin Sodium and Arthrotec, by gender? *:

female:

Asthma
Blood thyroid stimulating hormone increased
Body height decreased
Cardiac failure congestive
Carotid arteriosclerosis (plaque deposition in artery)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cervicobrachial syndrome (pain in neck and arm with changing location)
Chest pain
Confusional state

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Fall
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomyopathy (weakening of the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease

What are the common drug interactions of Warfarin Sodium and Arthrotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Back pain
Osteoporosis (bones weak and more likely to break)
Pneumonia
Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
Tricuspid valve incompetence (inefficient heart valve)
Thrombosis (formation of a blood clot inside a blood vessel)

30-39:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diarrhoea
Eye pain
Neutropenia (an abnormally low number of neutrophils)
Pain in face
Pain in limb
Rigors (an episode of shaking or exaggerated shivering)
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin disorder (skin disease)

40-49:

Contusion (a type of hematoma of tissue in which capillaries)
Fungal infection
International normalised ratio increased

50-59:

Oedema lower limb (fluid collection in tissue of lower leg)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Asthma
Cardiomyopathy (weakening of the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspnoea (difficult or laboured respiration)
Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)

60+:

Colitis (inflammation of colon)
Anaemia (lack of blood)
Dehydration (dryness resulting from the removal of water)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Pulmonary embolism (blockage of the main artery of the lung)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Blood albumin decreased
Blood pressure diastolic decreased

What are the existing conditions these people have? *

Depression: 15 people, 25.00%
High Blood Cholesterol: 14 people, 23.33%
High Blood Pressure: 12 people, 20.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 10 people, 16.67%
Colitis (inflammation of colon): 5 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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