Warfarin sodium and Excedrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Warfarin sodium (warfarin sodium) and Excedrin (acetaminophen; aspirin; caffeine). Common drug interactions include cardiac myxoma among females and influenza among males.

The phase IV clinical study analyzes what interactions people have when they take Warfarin sodium and Excedrin. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Warfarin sodium?

Warfarin sodium has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 71,174 Warfarin sodium users. Check the latest studies of Warfarin sodium.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

35 people who take Warfarin sodium and Excedrin together, and have interactions are studied.

Warfarin sodium and Excedrin drug interactions.

What are the common drug interactions of Warfarin Sodium and Excedrin, by gender? *:

female:

Cardiac myxoma (tumour of the heart in adults)
Confusional state
Deep brain stimulation
Diarrhoea
Dizziness
Fall
Nausea (feeling of having an urge to vomit)
Post-traumatic stress disorder
Somnolence (a state of near-sleep, a strong desire for sleep)
Thrombosis (formation of a blood clot inside a blood vessel)

male:

Influenza
Pneumonia
Thyroid disorder (thyroid diseases)

What are the common drug interactions of Warfarin Sodium and Excedrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Aphasia (damage to the parts of the brain that control language)
Emotional distress
Fibrin d dimer increased
General physical health deterioration (weak health status)
Hemiparesis (weakness on one side of the body)
Injury
Oedema peripheral (superficial swelling)
Pain in extremity
Superior sagittal sinus thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain)

30-39:

Diarrhoea
Dysphonia (speech disorder attributable to a disorder of phonation)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Pharyngolaryngeal pain

40-49:

Asthenia (weakness)
Erythema (redness of the skin)
Infusion site swelling
Nausea (feeling of having an urge to vomit)
Oedema mouth (swelling of mouth)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Skin irritation
Swelling
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting

50-59:

Exostosis (formation of new bone on the surface of a bone)
Gastrointestinal viral infection (virus infection of gastrointestinal tract)
Impulsive behaviour
Thrombosis (formation of a blood clot inside a blood vessel)
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups)
Viral infection
Cardiac myxoma (tumour of the heart in adults)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Post-traumatic stress disorder
Abnormal behaviour

60+:

Pneumonia
Influenza
Vaginal haemorrhage (vaginal bleeding)
Asthenia (weakness)
Back pain
Cataract (clouding of the lens inside the eye)
Constipation
Depression
Diarrhoea
Dizziness

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 11.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 11.43%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 3 people, 8.57%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 2 people, 5.71%
Pseudotumor Cerebri (increased pressure within the brain in the absence of a tumour): 2 people, 5.71%
Migraine (headache): 2 people, 5.71%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 5.71%
Birth Control: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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