Welchol and Bumex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Welchol (colesevelam hydrochloride) and Bumex (bumetanide). Common drug interactions include dyspnoea among females and haemoglobin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Welchol and Bumex. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

On Jul, 18, 2026

23 people who take Welchol and Bumex together, and have interactions are studied.

What are the common drug interactions of Welchol and Bumex, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Abdominal pain upper
Asthenia (weakness)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Angioedema (rapid swelling of the dermis)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood glucose increased
Cellulitis (infection under the skin)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Haemoglobin decreased
Dyspnoea (difficult or laboured respiration)
Capillary leak syndrome (capillary leaks plasma)
Cardiac failure congestive
Chills (felling of cold)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Decreased appetite
Device related infection
Erythema (redness of the skin)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Welchol and Bumex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

Arthralgia (joint pain)
Death
Dyspnoea (difficult or laboured respiration)
Fall
Haemoglobin decreased
Nausea (feeling of having an urge to vomit)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Abnormal faeces (abnormal stool)
Anxiety
Ascites (accumulation of fluid in the abdominal cavity)

60+:

Dyspnoea (difficult or laboured respiration)
Asthenia (weakness)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dry eye (lack of adequate tears)
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphonia (speech disorder attributable to a disorder of phonation)
Erythema (redness of the skin)
Gout (uric acid crystals building up in the body)
Haemoglobin decreased
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 2 people, 8.70%
Multiple Myeloma (cancer of the plasma cells): 2 people, 8.70%
Headache (pain in head): 2 people, 8.70%
Diabetes: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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