Welchol and Dapsone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Welchol (colesevelam hydrochloride) and Dapsone (dapsone). Common drug interactions include fall among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Welchol and Dapsone. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

What is Dapsone?

Dapsone has active ingredients of dapsone. It is often used in dermatitis herpetiformis. eHealthMe is studying from 11,732 Dapsone users. Check the latest studies of Dapsone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

20 people who take Welchol and Dapsone together, and have interactions are studied.

What are the common drug interactions of Welchol and Dapsone, by gender? *:

female:

Fall
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Headache (pain in head)
Viral infection
Blood iron decreased
Loss of consciousness
Urinary tract infection
Wheezing (a high-pitched whistling sound made while you breath)
Cyst (a closed sac)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperglycaemia (high blood sugar)
Kidney transplant rejection
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Thrombosis (formation of a blood clot inside a blood vessel)
Abdominal discomfort
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug ineffective

What are the common drug interactions of Welchol and Dapsone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Bradycardia (abnormally slow heart action)
Chest discomfort
Epstein-barr virus infection
Hypersensitivity
Intra-abdominal haematoma (intra-abdominal localized swelling filled with blood)
Kidney transplant rejection
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Thrombosis (formation of a blood clot inside a blood vessel)

20-29:

n/a

30-39:

Fall
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Headache (pain in head)
Viral infection
Blood iron decreased
Loss of consciousness
Urinary tract infection
Wheezing (a high-pitched whistling sound made while you breath)
Cyst (a closed sac)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperglycaemia (high blood sugar)
Hyperlipidaemia (presence of excess lipids in the blood)
Renal disorder (kidney disease)
Type 2 diabetes mellitus

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hepatitis b
Hepatitis c
Hiv infection
Hyperglycaemia (high blood sugar)
Hyperlipidaemia (presence of excess lipids in the blood)
Lung neoplasm malignant (cancer tumour of lung)
Pulmonary mass
Renal disorder (kidney disease)
Type 2 diabetes mellitus

60+:

Abdominal discomfort
Angina pectoris (chest pain due to ischemia of the heart muscle)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Neutropenia (an abnormally low number of neutrophils)
Oedema peripheral (superficial swelling)
Pain
Plasma cell myeloma (cancer that begins in plasma cells)
Pruritus (severe itching of the skin)
Skin discolouration (change of skin colour)
Skin hypertrophy (skin cells enlarges)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 45.00%
Headache (pain in head): 6 people, 30.00%
Sleep Disorder: 2 people, 10.00%
Dyspnea (difficult or laboured breathing): 2 people, 10.00%
Weakness: 1 person, 5.00%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.00%
Brain Neoplasm Malignant (brain cancer tumour): 1 person, 5.00%
Breast Lump (localized swelling that feels different from the surrounding breast tissue): 1 person, 5.00%
Chronic Renal Failure (kidney failure): 1 person, 5.00%
Fibrillary Glomerulonephritis (progressive renal dysfunction with deposit in glomeruli): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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