Welchol and Gleevec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Welchol (colesevelam hydrochloride) and Gleevec (imatinib mesylate). Common drug interactions include malaise among females and cerebral haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Welchol and Gleevec. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

On Jul, 21, 2026

17 people who take Welchol and Gleevec together, and have interactions are studied.

What are the common drug interactions of Welchol and Gleevec, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Flushing (the warm, red condition of human skin)
General physical health deterioration (weak health status)
Hip fracture
Migraine (headache)
Muscular weakness (muscle weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myalgia (muscle pain)
Vomiting
Nausea (feeling of having an urge to vomit)

male:

Cerebral haemorrhage (bleeding within the brain)
Haematochezia (passage of stools containing blood)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)
Pneumonia
Ulcer
Weight increased

What are the common drug interactions of Welchol and Gleevec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Arthralgia (joint pain)
Bone pain
Chest pain
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)

50-59:

Back pain
Haematochezia (passage of stools containing blood)
Hip fracture
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)
Oral candidiasis (fungal infection of mouth)
Rash
Weight increased

60+:

Ageusia (loss of taste functions of the tongue)
Cerebral haemorrhage (bleeding within the brain)
Pyrexia (fever)
Rash
Swelling face
Ulcer
Decreased appetite
Disease progression
Dysgeusia (disorder of the sense of taste)
Eye swelling

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 29.41%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 29.41%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 23.53%
Malignant Soft Tissue Neoplasm (cancer tumour of soft tissue): 2 people, 11.76%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 1 person, 5.88%
Polymyalgia Rheumatica (pain in many muscles): 1 person, 5.88%
Leukaemia (blood or bone marrow cancer): 1 person, 5.88%
Hiv Infection: 1 person, 5.88%
Gastrointestinal Stromal Tumor: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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