Xalatan and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xalatan (latanoprost) and Compazine (prochlorperazine maleate). Common drug interactions include general physical health deterioration among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Xalatan and Compazine. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in nausea and vomiting. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Aug, 02, 2026

77 people who take Xalatan and Compazine together, and have interactions are studied.

Xalatan and Compazine drug interactions.

What are the common drug interactions of Xalatan and Compazine, by gender? *:

female:

General physical health deterioration (weak health status)
Hypersensitivity
Hypertension (high blood pressure)
Infusion related reaction
Mass
Metastases to spine (cancer spreads to spine)
Neutropenia (an abnormally low number of neutrophils)
Oral disorder (mouth disease)
Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)

male:

Diarrhoea
Constipation
Groin pain
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypertransaminasaemia
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Metastases to bone marrow (cancer spreads to bone marrow)
Metastases to spine (cancer spreads to spine)
Neuropathy peripheral (surface nerve damage)
Oral candidiasis (fungal infection of mouth)

What are the common drug interactions of Xalatan and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaemia (lack of blood)
Blood calcium decreased
Blood sodium decreased
Blood urea increased
Enterococcus test positive
Hypoxia (low oxygen in tissues)
Intestinal obstruction
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Pneumonia

50-59:

Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic calcification (aortic calcification sign of heart valve disease)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Arthropathy
Asthenia (weakness)

60+:

Diarrhoea
Fatigue (feeling of tiredness)
Neutropenia (an abnormally low number of neutrophils)
Pain in extremity
Urinary tract infection
Anaemia (lack of blood)
Cough
Decreased appetite
Faecaloma (hard mass of fecal matter)
Mucosal inflammation (infection of mucous membrane)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 17 people, 22.08%
Multiple Myeloma (cancer of the plasma cells): 17 people, 22.08%
High Blood Pressure: 9 people, 11.69%
Pain: 8 people, 10.39%
Ovarian Cancer (cancer of ovary): 8 people, 10.39%
Insomnia (sleeplessness): 8 people, 10.39%
Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins): 7 people, 9.09%
Stress And Anxiety: 5 people, 6.49%
Hypersensitivity: 4 people, 5.19%
Diarrhea: 4 people, 5.19%

* Approximation only. Some reports may have incomplete information.

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