Xalatan and Desyrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xalatan (latanoprost) and Desyrel (trazodone hydrochloride). Common drug interactions include nephrolithiasis among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Xalatan and Desyrel. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

On Jul, 29, 2026

33 people who take Xalatan and Desyrel together, and have interactions are studied.

What are the common drug interactions of Xalatan and Desyrel, by gender? *:

female:

Nephrolithiasis (calculi in the kidneys)
Neuropathy peripheral (surface nerve damage)
Neutropenia (an abnormally low number of neutrophils)
Osteoporosis (bones weak and more likely to break)
Pain
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Purpura senile (skin condition in which areas of the skin develop a purplish or reddish-brown appearance due to bleeding of small blood vessels underneath)
Rash

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Pathological fracture (broken bone caused by disease)
Renal impairment (severely reduced kidney function)
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
Thrombocytopenia (decrease of platelets in blood)
Tooth disorder (tooth disease)
Tooth injury
Tooth loss
Blood bicarbonate decreased

What are the common drug interactions of Xalatan and Desyrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood cholesterol increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hypertension (high blood pressure)
Neuropathy peripheral (surface nerve damage)
Purpura senile (skin condition in which areas of the skin develop a purplish or reddish-brown appearance due to bleeding of small blood vessels underneath)
Renal failure (kidney dysfunction)
Resorption bone increased
Tarsal tunnel syndrome (a condition that is caused by compression of the tibial nerve or its associated branches as the nerve)

40-49:

Therapeutic response unexpected

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Chronic kidney disease
Emotional distress
Hip fracture
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Renal impairment (severely reduced kidney function)
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)

60+:

Death
Blood glucose fluctuation
Aggression
Agitation (state of anxiety or nervous excitement)
Asthma
Blood bicarbonate decreased
Blood glucose increased
Blood pressure increased
Blood thyroid stimulating hormone increased
Blood urea nitrogen/creatinine ratio increased

What are the existing conditions these people have? *

Pain: 11 people, 33.33%
Stress And Anxiety: 8 people, 24.24%
Muscle Spasms (muscle contraction): 7 people, 21.21%
Nausea (feeling of having an urge to vomit): 6 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 18.18%
Diabetes: 6 people, 18.18%
High Blood Pressure: 6 people, 18.18%
High Blood Cholesterol: 5 people, 15.15%
Multiple Myeloma (cancer of the plasma cells): 5 people, 15.15%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 12.12%

* Approximation only. Some reports may have incomplete information.

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