Xalatan and Lidoderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xalatan (latanoprost) and Lidoderm (lidocaine). Common drug interactions include depression among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Xalatan and Lidoderm. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.

On Jul, 13, 2026

90 people who take Xalatan and Lidoderm together, and have interactions are studied.

What are the common drug interactions of Xalatan and Lidoderm, by gender? *:

female:

Depression
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Fear
Fracture displacement
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Osteonecrosis (death of bone)
Peripheral vascular disorder
Spinal compression fracture (fracture due to spinal compression on bone)

male:

Pneumonia
Disease progression
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hypotension (abnormally low blood pressure)
Metastases to adrenals (cancer spreads to adrenal gland of kidney)
Nausea (feeling of having an urge to vomit)
Urinary tract infection
Weight decreased
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Anaemia (lack of blood)

What are the common drug interactions of Xalatan and Lidoderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Urinary tract infection
Bacteraemia (presence of bacteria in the blood)
Encephalitis (inflammation of the brain)
Infected skin ulcer
Klebsiella infection
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Osteomyelitis (infection of bone)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

30-39:

n/a

40-49:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anaemia (lack of blood)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest discomfort
Hot flush (sudden feelings of heat)
Hypersensitivity

50-59:

Vision blurred
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Blood glucose increased
Depression
Fall
Fatigue (feeling of tiredness)
Fear
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)

60+:

Fall
Femur fracture
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Spinal compression fracture (fracture due to spinal compression on bone)
Impaired healing
Metastatic neoplasm (spreadable cancer tumour)
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pathological fracture (broken bone caused by disease)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)

What are the existing conditions these people have? *

High Blood Cholesterol: 9 people, 10.00%
Multiple Myeloma (cancer of the plasma cells): 8 people, 8.89%
Back Pain: 8 people, 8.89%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 7.78%
Diabetes: 7 people, 7.78%
Stress And Anxiety: 6 people, 6.67%
Insomnia (sleeplessness): 6 people, 6.67%
Osteoporosis (bones weak and more likely to break): 5 people, 5.56%
Muscle Spasms (muscle contraction): 5 people, 5.56%
Constipation: 5 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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