Xalatan and Propulsid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xalatan (latanoprost) and Propulsid (cisapride monohydrate). Common drug interactions include gastroenteritis among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Xalatan and Propulsid. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.



On Aug, 02, 2026

23 people who take Xalatan and Propulsid together, and have interactions are studied.

Xalatan and Propulsid drug interactions.

What are the common drug interactions of Xalatan and Propulsid, by gender? *:

female:

  1. Gastroenteritis (inflammation of stomach and intestine)
  2. Gastrointestinal pain
  3. Haematemesis (vomiting of blood)
  4. Haematuria (presence of blood in urine)
  5. Headache (pain in head)
  6. Herpes zoster
  7. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  8. Hypermetropia (abnormal condition in which vision for distant objects is better than for near objects)
  9. Hypersensitivity
  10. Hypertension (high blood pressure)

male:

  1. Cardiac failure congestive
  2. Dyspnoea (difficult or laboured respiration)
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Dyskinesia (abnormality or impairment of voluntary movement)
  5. Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
  6. Endocarditis bacterial (an inflammation of the inner layer of the heart by bacterial infection)
  7. Fatigue (feeling of tiredness)
  8. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  9. Left ventricular failure (left ventricle fails to contract forcefully)
  10. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Xalatan and Propulsid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Back pain
  2. Blood pressure decreased
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Peripheral nerve injury
  5. Pyrexia (fever)
  6. Septicaemia streptococcal (blood infection with bacteria)
  7. Spinal fracture (fracture in one of vertebrae)

40-49:

  1. Gastric mucosal hypertrophy (inflammation and ulcers (breaks on the skin or on the surface of an organ) of the mucosa (inner lining) of the stomach)
  2. Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
  3. Gastroenteritis (inflammation of stomach and intestine)
  4. Gastrointestinal pain
  5. Haematemesis (vomiting of blood)
  6. Haematuria (presence of blood in urine)
  7. Headache (pain in head)
  8. Herpes zoster
  9. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  10. Hyperglycaemia (high blood sugar)

50-59:

  1. Electrocardiogram qt prolonged
  2. Cardiac failure congestive
  3. Dyspnoea (difficult or laboured respiration)
  4. Mitral valve incompetence (inefficient heart valve)
  5. Angina pectoris (chest pain due to ischemia of the heart muscle)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Cardiomyopathy (weakening of the heart muscle)
  8. Chest pain
  9. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  10. Dyskinesia (abnormality or impairment of voluntary movement)

60+:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Hypoglycaemia (deficiency of glucose in the bloodstream)
  3. Fatigue (feeling of tiredness)
  4. Hyperglycaemia (high blood sugar)
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  6. Ketoacidosis (high concentrations of ketone bodies in blood)
  7. Loss of consciousness
  8. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  9. Sedation
  10. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the existing conditions these people have? *

  1. Pain: 4 people, 17.39%
  2. Gastrointestinal Motility Disorder (abnormal intestinal contractions): 4 people, 17.39%
  3. Constipation: 4 people, 17.39%
  4. Seasonal Allergy (allergic condition due to certain season): 2 people, 8.70%
  5. Rashes (redness): 2 people, 8.70%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 8.70%
  7. Nausea (feeling of having an urge to vomit): 2 people, 8.70%
  8. Joint Pain: 2 people, 8.70%
  9. Itching: 2 people, 8.70%
  10. Erection Problems: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Xalatan and Propulsid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xalatan and Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xalatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xalatan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Propulsid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on latanoprost and cisapride monohydrate (the active ingredients of Xalatan and Propulsid, respectively), and Xalatan and Propulsid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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