Xeloda and Roxicet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xeloda (capecitabine) and Roxicet (acetaminophen; oxycodone hydrochloride). Common drug interactions include metastases to bone among females and mucosal inflammation among males.

The phase IV clinical study analyzes what interactions people have when they take Xeloda and Roxicet. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Xeloda?

Xeloda has active ingredients of capecitabine. It is often used in colon cancer. eHealthMe is studying from 46,649 Xeloda users. Check the latest studies of Xeloda.

What is Roxicet?

Roxicet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 2,254 Roxicet users. Check the latest studies of Roxicet.

On Jul, 12, 2026

26 people who take Xeloda and Roxicet together, and have interactions are studied.

What are the common drug interactions of Xeloda and Roxicet, by gender? *:

female:

Metastases to bone (cancer spreads to bone)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Hepatic cyst
Tooth loss
Anxiety
Bone pain
Cellulitis (infection under the skin)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain in jaw
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

male:

Mucosal inflammation (infection of mucous membrane)
Actinomycotic skin infection (infectious and inflammatory diseases affect the skin and the oral mucosa)
Back pain
Bone disorder
Bone pain
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cellulitis (infection under the skin)
Cervix inflammation
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Xeloda and Roxicet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acute sinusitis
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Bone disorder
Bone pain
Cellulitis (infection under the skin)
Cervix inflammation
Dental caries
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)

50-59:

Emotional distress
Hepatic cyst
Infection
Injury
Metastases to bone (cancer spreads to bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Scar
Tooth loss
Gingival swelling (gums swelling)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

60+:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Exposed bone in jaw
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatic steatosis (fatty liver disease)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Injury
Intervertebral disc protrusion (spinal disc protrusion)
Neoplasm progression (growth of tumour)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 11 people, 42.31%
Breast Cancer: 7 people, 26.92%
Anaemia (lack of blood): 7 people, 26.92%
Breast Cancer Metastatic: 5 people, 19.23%

* Approximation only. Some reports may have incomplete information.

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