Xenical and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xenical (orlistat) and Azithromycin (azithromycin). Common drug interactions include drug ineffective among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Xenical and Azithromycin. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Xenical?

Xenical has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 11,722 Xenical users. Check the latest studies of Xenical.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

On Aug, 04, 2026

33 people who take Xenical and Azithromycin together, and have interactions are studied.

Xenical and Azithromycin drug interactions.

What are the common drug interactions of Xenical and Azithromycin, by gender? *:

female:

Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Eating disorder
Hallucination (an experience involving the perception of something not present)
Impaired driving ability
Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia)
Muscle injury
Muscle spasms (muscle contraction)
Occult blood (blood in the faeces that is not visibly apparent)
Pain

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Diabetes mellitus inadequate control
Feeling cold
Foot fracture
Frostbite (damage is caused to skin and other tissues due to freezing)
Gout (uric acid crystals building up in the body)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)

What are the common drug interactions of Xenical and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood glucose increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Chest discomfort
Cholecystitis (infection of gallbladder)

30-39:

Abdominal pain
Acne (skin problems that cause pimples)
Anaemia (lack of blood)
Arthralgia (joint pain)
Blood cholesterol increased
Blood glucose increased
Blood pressure increased
Blood triglycerides increased
Contusion (a type of hematoma of tissue in which capillaries)
Dermatitis allergic (inflammation of the skin due allergic reaction)

40-49:

Tendon injury
Tendonitis (a condition that causes pain and swelling of tendons)
Weight increased
Blood cholesterol increased
Abdominal pain upper
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood glucose decreased
Blood glucose increased
Bone density decreased

50-59:

Chronic kidney disease
Alopecia (absence of hair from areas of the body)
Anxiety
Asthenia (weakness)
Breast cancer
Cellulitis (infection under the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chemotherapy
Chest pain
Compression fracture (fracture due to pressure caused by injury)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chronic kidney disease
Prostatomegaly (enlargement of the prostate)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Urinary retention (the inability to completely or partially empty the bladder)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress

What are the existing conditions these people have? *

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 14 people, 42.42%
Pain: 10 people, 30.30%
High Blood Pressure: 9 people, 27.27%
Depression: 8 people, 24.24%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 24.24%
Urinary Tract Infection: 5 people, 15.15%
Mixed Incontinence (a combination of stress and urge incontinence): 5 people, 15.15%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 15.15%
Hypertriglyceridaemia (excess of triglycerides in the blood): 5 people, 15.15%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 15.15%

* Approximation only. Some reports may have incomplete information.

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