Xenical and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xenical (orlistat) and Colace (docusate ). Common drug interactions include sinus tachycardia among females and hypoglycaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Xenical and Colace. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Xenical?

Xenical has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 11,722 Xenical users. Check the latest studies of Xenical.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

17 people who take Xenical and Colace together, and have interactions are studied.

What are the common drug interactions of Xenical and Colace, by gender? *:

female:

Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Acute myocardial infarction (acute heart attack)
Angiopathy (generic term for a disease of the blood vessels)
Arteriosclerosis (thickening and hardening of arteries)
Asthenia (weakness)
Bladder disorder
Blood potassium decreased
Blood potassium increased
Eclampsia (acute and life-threatening complication of pregnancy)
Electrocardiogram qt prolonged

male:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Sluggishness (lacking alertness)
Pericardial effusion (fluid around the heart)
Weight increased
Arthralgia (joint pain)
Back pain
Blood cholesterol increased
Blood potassium decreased
Blood testosterone decreased
Blood uric acid increased

What are the common drug interactions of Xenical and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Menstruation irregular
Orthopnoea (shortness of breath (dyspnea) when lying down)
Pericardial effusion (fluid around the heart)
Polycystic ovaries (cysts in the ovaries that occurs when the follicle stops developing)
Renal cancer (cancer of kidney)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Subdural haemorrhage (bleeding between the skull and the surface of the brain)
Upper respiratory tract infection
Abdominal pain upper
Atelectasis (partial or complete collapse of the lung)

30-39:

n/a

40-49:

Angiopathy (generic term for a disease of the blood vessels)
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Arthralgia (joint pain)
Back pain
Blood cholesterol increased
Blood potassium decreased
Blood testosterone decreased
Blood uric acid increased
Bone disorder
Calculus bladder (bladder stone)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Drug ineffective
Headache (pain in head)
Pericardial effusion (fluid around the heart)
Weight increased
Abdominal distension
Abdominal pain
Cardiac flutter (abnormal heart rhythm)
Chest pain
Chorea (abnormal involuntary movement disorder)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
Peripartum Cardiomyopathy (deterioration in cardiac function presenting typically between the last month of pregnancy and up to five months postpartum): 2 people, 11.76%
Depression: 2 people, 11.76%
Weight Decreased: 1 person, 5.88%
Pituitary Tumor: 1 person, 5.88%
Parkinson's Disease: 1 person, 5.88%
Osteoporosis (bones weak and more likely to break): 1 person, 5.88%
Indigestion: 1 person, 5.88%
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 1 person, 5.88%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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