Xopenex and Aerobid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xopenex (levalbuterol hydrochloride) and Aerobid (flunisolide). Common drug interactions include aggression among females and international normalised ratio decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Xopenex and Aerobid. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Xopenex?

Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.

What is Aerobid?

Aerobid has active ingredients of flunisolide. eHealthMe is studying from 1,126 Aerobid users. Check the latest studies of Aerobid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

15 people who take Xopenex and Aerobid together, and have interactions are studied.

Xopenex and Aerobid drug interactions.

What are the common drug interactions of Xopenex and Aerobid, by gender? *:

female:

  1. Aggression
  2. Cardiac failure congestive
  3. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  4. Constipation
  5. Dehydration (dryness resulting from the removal of water)
  6. Diarrhoea
  7. Gastric ulcer (stomach ulcer)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

male:

  1. International normalised ratio decreased
  2. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  3. Glycosylated haemoglobin increased
  4. Hypotension (abnormally low blood pressure)
  5. International normalised ratio increased
  6. Medical device complication
  7. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  8. Oedema peripheral (superficial swelling)
  9. Pneumonia
  10. Syncope (loss of consciousness with an inability to maintain postural tone)

What are the common drug interactions of Xopenex and Aerobid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

50-59:

  1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  2. Ataxia (loss of full control of bodily movements)
  3. Balance disorder
  4. Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
  5. Cerebral atrophy (decrement in size of brain)
  6. Cerebral infarction (less blood supply to brain resulting tissue damage)
  7. Cerebral small vessel ischaemic disease (inadequate blood supply to small blood vessel of brain)
  8. Confusional state
  9. Dysarthria (speech disorder)
  10. Encephalomalacia (localized softening of the brain substance, due to haemorrhage or inflammation)

60+:

  1. Aggression
  2. Cardiac failure congestive
  3. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  4. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  5. Ventricular fibrillation (abnormally irregular heart rhythm)
  6. Weight decreased
  7. Anxiety
  8. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  9. Pain
  10. Peripheral vascular disorder

What are the existing conditions these people have? *

  1. Arrhythmias (irregular heartbeat): 5 people, 33.33%
  2. Eye Disorder: 3 people, 20.00%
  3. Fever: 3 people, 20.00%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 20.00%
  5. Body Temperature Increased: 3 people, 20.00%
  6. Depression: 3 people, 20.00%
  7. Dyspnea (difficult or laboured breathing): 3 people, 20.00%
  8. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 20.00%
  9. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 20.00%
  10. Aneurysm (enlargement of an artery caused by a weakening of the artery wall): 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Xopenex and Aerobid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xopenex and Aerobid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xopenex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aerobid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xopenex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aerobid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levalbuterol hydrochloride and flunisolide (the active ingredients of Xopenex and Aerobid, respectively), and Xopenex and Aerobid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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