Xopenex and Duragesic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xopenex (levalbuterol hydrochloride) and Duragesic (fentanyl). Common drug interactions include pyrexia among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Xopenex and Duragesic. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Xopenex?

Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.

What is Duragesic?

Duragesic has active ingredients of fentanyl. eHealthMe is studying from 66,597 Duragesic users. Check the latest studies of Duragesic.

On Jul, 19, 2026

83 people who take Xopenex and Duragesic together, and have interactions are studied.

Xopenex and Duragesic drug interactions.

What are the common drug interactions of Xopenex and Duragesic, by gender? *:

female:

Pyrexia (fever)
Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Depression
Pleural effusion (water on the lungs)
Respiratory failure (inadequate gas exchange by the respiratory system)
Wheezing (a high-pitched whistling sound made while you breath)
Foot deformity (functional disability of foot)
Abdominal pain
Fatigue (feeling of tiredness)

male:

Confusional state
Anxiety
Fall
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hallucination (an experience involving the perception of something not present)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Neoplasm malignant (cancer tumour)
Respiratory failure (inadequate gas exchange by the respiratory system)
Screaming (a long loud piercing cry)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)

What are the common drug interactions of Xopenex and Duragesic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Arthralgia (joint pain)
Conjunctivitis (pink eye)
Deformity (disfigurement)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dry skin
Exfoliative rash (scaly red generalized skin rash)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
General physical health deterioration (weak health status)
Joint stiffness
Mobility decreased (ability to move is reduced)

20-29:

n/a

30-39:

Infection
Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)
Acne (skin problems that cause pimples)
Alopecia (absence of hair from areas of the body)
Anal fissure
Anogenital warts
Anxiety
Bacterial infection
Bone erosion

40-49:

Cough
Dyspnoea (difficult or laboured respiration)
Intervertebral disc protrusion (spinal disc protrusion)
Pain
Atelectasis (partial or complete collapse of the lung)
Blood glucose increased
Breath sounds
Chest pain
Diarrhoea
Gastritis (inflammation of stomach)

50-59:

Anxiety
Blood alkaline phosphatase increased
Cellulitis (infection under the skin)
Chest pain
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypokalaemia (low potassium)
Neck pain

60+:

Dizziness
Drug ineffective
Vomiting
Abnormal behaviour
Dyspnoea (difficult or laboured respiration)
Fall
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hallucination (an experience involving the perception of something not present)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Headache (pain in head)

What are the existing conditions these people have? *

Pain: 26 people, 31.33%
Back Pain: 10 people, 12.05%
High Blood Pressure: 9 people, 10.84%
Osteoporosis (bones weak and more likely to break): 8 people, 9.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 8.43%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 8.43%
Cough: 7 people, 8.43%
Nausea (feeling of having an urge to vomit): 7 people, 8.43%
Stress And Anxiety: 7 people, 8.43%
Migraine (headache): 7 people, 8.43%

* Approximation only. Some reports may have incomplete information.

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