Xtampza er and Olanzapine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xtampza er (oxycodone) and Olanzapine (olanzapine). Common drug interactions include hypokalaemia among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Xtampza er and Olanzapine. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Xtampza er?

Xtampza er has active ingredients of oxycodone. eHealthMe is studying from 1,502 Xtampza er users. Check the latest studies of Xtampza er.

What is Olanzapine?

Olanzapine has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 69,242 Olanzapine users. Check the latest studies of Olanzapine.



On Jul, 17, 2026

13 people who take Xtampza er and Olanzapine together, and have interactions are studied.

Xtampza er and Olanzapine drug interactions.

What are the common drug interactions of Xtampza Er and Olanzapine, by gender? *:

female:

  1. Hypokalaemia (low potassium)
  2. Osteoporosis (bones weak and more likely to break)
  3. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Constipation

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fatigue (feeling of tiredness)
  3. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. White blood cell count decreased
  6. Anxiety
  7. Death
  8. Drug ineffective

What are the common drug interactions of Xtampza Er and Olanzapine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Drug ineffective

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fatigue (feeling of tiredness)
  3. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. White blood cell count decreased
  6. Anxiety
  7. Death
  8. Hypokalaemia (low potassium)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 5 people, 38.46%
  2. Multiple Myeloma (cancer of the plasma cells): 4 people, 30.77%
  3. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.69%
  4. Stress And Anxiety: 1 person, 7.69%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.69%
  6. Pain: 1 person, 7.69%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.69%
  8. Malignant Melanoma (skin cancer rises from melancytes): 1 person, 7.69%
  9. Dyspnea (difficult or laboured breathing): 1 person, 7.69%
  10. Depression: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Xtampza er and Olanzapine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xtampza er and Olanzapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xtampza er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Olanzapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xtampza er and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Olanzapine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on oxycodone and olanzapine (the active ingredients of Xtampza er and Olanzapine, respectively), and Xtampza er and Olanzapine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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