Xylocaine and Clexane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xylocaine (lidocaine hydrochloride) and Clexane (enoxaparin sodium). Common drug interactions include abdominal pain upper among females and blood albumin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Xylocaine and Clexane. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Xylocaine?

Xylocaine has active ingredients of lidocaine hydrochloride. eHealthMe is studying from 5,716 Xylocaine users. Check the latest studies of Xylocaine.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.



On Jul, 11, 2026

13 people who take Xylocaine and Clexane together, and have interactions are studied.

Xylocaine and Clexane drug interactions.

What are the common drug interactions of Xylocaine and Clexane, by gender? *:

female:

  1. Abdominal pain upper
  2. Decreased appetite
  3. Dehydration (dryness resulting from the removal of water)
  4. Diarrhoea
  5. Eating disorder
  6. Febrile neutropenia (fever with reduced white blood cells)
  7. Hypokalaemia (low potassium)
  8. Mucosal inflammation (infection of mucous membrane)
  9. Nausea (feeling of having an urge to vomit)
  10. Paraneoplastic syndrome (symptom that is the consequence of the presence of cancer in the body)

male:

  1. Blood albumin decreased
  2. Blood alkaline phosphatase increased
  3. Blood sodium decreased
  4. Dehydration (dryness resulting from the removal of water)
  5. Disease progression
  6. Gamma-glutamyltransferase increased
  7. Haematocrit decreased
  8. Haemoglobin decreased
  9. Haemorrhage intracranial (bleeding within the skull)
  10. Headache (pain in head)

What are the common drug interactions of Xylocaine and Clexane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  3. Ileus (a painful obstruction of the ileum or other part of the intestine)

50-59:

  1. Paraneoplastic syndrome (symptom that is the consequence of the presence of cancer in the body)
  2. Colitis (inflammation of colon)
  3. Pneumatosis intestinalis (air or gas in an intestine)

60+:

  1. Abdominal pain upper
  2. Decreased appetite
  3. Hypotension (abnormally low blood pressure)
  4. Incision site infection (infection at incision site)
  5. Lung infection
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Spinal fracture (fracture in one of vertebrae)
  8. General physical health deterioration (weak health status)
  9. Haemorrhage intracranial (bleeding within the skull)
  10. Interstitial lung disease

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 9 people, 69.23%
  2. High Blood Pressure: 6 people, 46.15%
  3. Abdominal Pain Upper: 5 people, 38.46%
  4. Anaemia (lack of blood): 5 people, 38.46%
  5. Diarrhea: 5 people, 38.46%
  6. Constipation: 5 people, 38.46%
  7. Joint Pain: 4 people, 30.77%
  8. Cough: 4 people, 30.77%
  9. Swallowing Pain Or Burning: 4 people, 30.77%
  10. Dehydration (dryness resulting from the removal of water): 4 people, 30.77%

* Approximation only. Some reports may have incomplete information.

Do you take Xylocaine and Clexane?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xylocaine and Clexane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xylocaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clexane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xylocaine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clexane and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lidocaine hydrochloride and enoxaparin sodium (the active ingredients of Xylocaine and Clexane, respectively), and Xylocaine and Clexane (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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