Xywav and Hydrocodone bitartrate and acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xywav (calcium oxybate; magnesium oxybate; potassium oxybate; sodium oxybate) and Hydrocodone bitartrate and acetaminophen (acetaminophen; hydrocodone bitartrate). Common drug interactions include asthma among females and musculoskeletal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Xywav and Hydrocodone bitartrate and acetaminophen. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Xywav?

Xywav has active ingredients of calcium oxybate; magnesium oxybate; potassium oxybate; sodium oxybate. eHealthMe is studying from 7,134 Xywav users. Check the latest studies of Xywav.

What is Hydrocodone bitartrate and acetaminophen?

Hydrocodone bitartrate and acetaminophen has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 67,662 Hydrocodone bitartrate and acetaminophen users. Check the latest studies of Hydrocodone bitartrate and acetaminophen.

On Jul, 17, 2026

23 people who take Xywav and Hydrocodone bitartrate and acetaminophen together, and have interactions are studied.

Xywav and Hydrocodone bitartrate and acetaminophen drug interactions.

What are the common drug interactions of Xywav and Hydrocodone Bitartrate And Acetaminophen, by gender? *:

female:

Asthma
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Heart rate increased
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hyperkeratosis (thickening of the outer layer of the skin)
Mycotic allergy (fungal allergy)
Neck pain
Spinal osteoarthritis (joint cartilage loss in spine)
Thrombosis (formation of a blood clot inside a blood vessel)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

male:

Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)

What are the common drug interactions of Xywav and Hydrocodone Bitartrate And Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthropathy
Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
Sinusitis (inflammation of sinus)
Hysterectomy

40-49:

Anxiety disorder
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug intolerance (drug sensitivity)
Oral surgery
Anaemia (lack of blood)
Bipolar disorder (mood disorder)
Surgery
Anxiety
Asthma
Anger

50-59:

Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Hypoxia (low oxygen in tissues)
Surgery
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 20 people, 86.96%
Drowsiness: 16 people, 69.57%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 65.22%
Joint Pain: 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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