Xyzal and Evening primrose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xyzal (levocetirizine dihydrochloride) and Evening primrose (evening primrose oil). Common drug interactions include arthralgia among females.

The phase IV clinical study analyzes what interactions people have when they take Xyzal and Evening primrose. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Xyzal?

Xyzal has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 21,479 Xyzal users. Check the latest studies of Xyzal.

What is Evening primrose?

Evening primrose has active ingredients of evening primrose oil. It is often used in breast pain. eHealthMe is studying from 1,794 Evening primrose users. Check the latest studies of Evening primrose.

On Jul, 20, 2026

14 people who take Xyzal and Evening primrose together, and have interactions are studied.

Xyzal and Evening primrose drug interactions.

What are the common drug interactions of Xyzal and Evening Primrose, by gender? *:

female:

Arthralgia (joint pain)
Back pain
Insomnia (sleeplessness)
Nephrolithiasis (calculi in the kidneys)
Overdose
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Abdominal discomfort
Anaphylactic reaction (serious allergic reaction)
Angioedema (rapid swelling of the dermis)
Asthma exercise induced

male:

n/a

What are the common drug interactions of Xyzal and Evening Primrose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dehydration (dryness resulting from the removal of water)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dry eye (lack of adequate tears)
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)
Ear pain
Eye pain
Eye swelling
Impaired driving ability

40-49:

n/a

50-59:

Arteriovenous malformation
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Insomnia (sleeplessness)
Overdose
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

60+:

Anaphylactic reaction (serious allergic reaction)
Angioedema (rapid swelling of the dermis)

What are the existing conditions these people have? *

Immunodeficiency: 5 people, 35.71%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 21.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 21.43%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 14.29%
Vitamin B12 Deficiency: 1 person, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
Multiple Allergies (allergy to multiple agents): 1 person, 7.14%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 1 person, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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