Xyzal and Multaq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xyzal (levocetirizine dihydrochloride) and Multaq (dronedarone hydrochloride). Common drug interactions include basal cell carcinoma among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Xyzal and Multaq. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Xyzal?

Xyzal has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 21,479 Xyzal users. Check the latest studies of Xyzal.

What is Multaq?

Multaq has active ingredients of dronedarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 11,053 Multaq users. Check the latest studies of Multaq.

On Jul, 11, 2026

15 people who take Xyzal and Multaq together, and have interactions are studied.

What are the common drug interactions of Xyzal and Multaq, by gender? *:

female:

Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Decreased appetite
Discomfort
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Glossodynia (a burning or painful sensation in the tongue)
Haemorrhage intracranial (bleeding within the skull)
Hepatocellular injury (liver injury)

male:

Chest pain
Drug hypersensitivity
Drug ineffective
Gastrointestinal pain
Pain
Psoriasis (immune-mediated disease that affects the skin)

What are the common drug interactions of Xyzal and Multaq, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Glossodynia (a burning or painful sensation in the tongue)
Haemorrhage intracranial (bleeding within the skull)
Hepatocellular injury (liver injury)
Hypertrophy of tongue papillae (increase in the volume of tongue papillae due to the enlargement of its component cells)
Neuropathy peripheral (surface nerve damage)
Psoriasis (immune-mediated disease that affects the skin)
Rectal abscess (pus in rectum)

What are the existing conditions these people have? *

Asthma: 3 people, 20.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 20.00%
Multiple Myeloma (cancer of the plasma cells): 3 people, 20.00%
Immunodeficiency Common Variable: 2 people, 13.33%
Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 6.67%
Heart Rate Irregular: 1 person, 6.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 6.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.67%
Depression: 1 person, 6.67%
Hypersensitivity: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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