Xyzal and Nitrostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xyzal (levocetirizine dihydrochloride) and Nitrostat (nitroglycerin). Common drug interactions include bronchitis among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Xyzal and Nitrostat. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Xyzal?

Xyzal has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 21,479 Xyzal users. Check the latest studies of Xyzal.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

On Jul, 10, 2026

57 people who take Xyzal and Nitrostat together, and have interactions are studied.

What are the common drug interactions of Xyzal and Nitrostat, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dermal cyst
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug ineffective
Essential hypertension (primary hypertension)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Gastric haemorrhage (bleeding stomach)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hypertension (high blood pressure)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Hypersensitivity
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Nausea (feeling of having an urge to vomit)
Respiratory disorder (respiratory disease)
Urticaria (rash of round, red welts on the skin that itch intensely)
Back pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Xyzal and Nitrostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Asthenia (weakness)
Blood pressure decreased
Erythema (redness of the skin)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Hypersensitivity
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Nausea (feeling of having an urge to vomit)
Respiratory disorder (respiratory disease)

50-59:

Fluid retention (an abnormal accumulation of fluid in the blood)
Glycosylated haemoglobin
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hypertension (high blood pressure)
Lymphoedema (localized fluid retention and tissue swelling)
Memory impairment
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pericardial effusion (fluid around the heart)
Renal failure (kidney dysfunction)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Neck pain
Ocular hyperaemia (an abnormally large amount of blood in eye)
Pain
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Arthropathy
Asthma

What are the existing conditions these people have? *

Pain: 9 people, 15.79%
High Blood Pressure: 9 people, 15.79%
Hypersensitivity: 8 people, 14.04%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 14.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 14.04%
High Blood Cholesterol: 7 people, 12.28%
Back Pain: 6 people, 10.53%
Cardiac Disorder: 6 people, 10.53%
Type 2 Diabetes: 6 people, 10.53%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 6 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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