Yaz and Levonorgestrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Yaz (drospirenone; ethinyl estradiol) and Levonorgestrel (levonorgestrel). Common drug interactions include cholecystitis chronic among females.

The phase IV clinical study analyzes what interactions people have when they take Yaz and Levonorgestrel. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.

What is Levonorgestrel?

Levonorgestrel has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 4,186 Levonorgestrel users. Check the latest studies of Levonorgestrel.

On Jul, 26, 2026

17 people who take Yaz and Levonorgestrel together, and have interactions are studied.

Yaz and Levonorgestrel drug interactions.

What are the common drug interactions of Yaz and Levonorgestrel, by gender? *:

female:

Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder disorder
Dizziness
Drooling (drop saliva uncontrollably from the mouth)
Drug ineffective
Enuresis (repeated inability to control urination)
Fungal infection
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypersensitivity
Hypomenorrhoea (a diminution of the menstrual flow or a shortening of the duration of menstruation)

male:

n/a

What are the common drug interactions of Yaz and Levonorgestrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Menstruation delayed (late menstruation cycle)
Pain

20-29:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypomenorrhoea (a diminution of the menstrual flow or a shortening of the duration of menstruation)
Menstruation delayed (late menstruation cycle)
Menstruation irregular
Nausea (feeling of having an urge to vomit)
Post abortion haemorrhage
Vomiting
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Abdominal pain upper
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)

30-39:

Abdominal pain upper
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder disorder

40-49:

Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder disorder

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 11.76%
Swelling: 2 people, 11.76%
Stress And Anxiety: 2 people, 11.76%
Neuralgia (pain in one or more nerves): 2 people, 11.76%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 11.76%
Multiple Allergies (allergy to multiple agents): 2 people, 11.76%
Itching: 2 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
Depression: 2 people, 11.76%
Cystitis Interstitial (unknown cause characterized by bladder pain): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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