Yervoy and Epinastine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Yervoy (ipilimumab) and Epinastine hydrochloride (epinastine hydrochloride). Common drug interactions include adrenocortical insufficiency acute among males.

The phase IV clinical study analyzes what interactions people have when they take Yervoy and Epinastine hydrochloride. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Yervoy?

Yervoy has active ingredients of ipilimumab. eHealthMe is studying from 26,662 Yervoy users. Check the latest studies of Yervoy.

What is Epinastine hydrochloride?

Epinastine hydrochloride has active ingredients of epinastine hydrochloride. eHealthMe is studying from 1,582 Epinastine hydrochloride users. Check the latest studies of Epinastine hydrochloride.



On Jul, 12, 2026

14 people who take Yervoy and Epinastine hydrochloride together, and have interactions are studied.

Yervoy and Epinastine hydrochloride drug interactions.

What are the common drug interactions of Yervoy and Epinastine Hydrochloride, by gender? *:

female:

n/a

male:

  1. Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
  2. Altered state of consciousness (altered state of mind)
  3. Tumour haemorrhage (bleeding from tumour)
  4. Cytomegalovirus enterocolitis (virus infection of intestine and colon)
  5. Polymyalgia rheumatica (pain in many muscles)
  6. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  8. Death
  9. Device related infection
  10. Encephalitis (inflammation of the brain)

What are the common drug interactions of Yervoy and Epinastine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  2. Platelet count decreased
  3. Speech disorder
  4. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  5. Tumour haemorrhage (bleeding from tumour)
  6. Altered state of consciousness (altered state of mind)
  7. Device related infection
  8. Encephalitis (inflammation of the brain)

60+:

  1. Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
  2. Death
  3. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  4. Cytomegalovirus enterocolitis (virus infection of intestine and colon)
  5. Polymyalgia rheumatica (pain in many muscles)
  6. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 10 people, 71.43%
  2. Renal Cancer Recurrent (cancer of kidney repeat): 2 people, 14.29%
  3. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 14.29%
  4. Nausea (feeling of having an urge to vomit): 1 person, 7.14%
  5. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Yervoy and Epinastine hydrochloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Yervoy and Epinastine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Yervoy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Epinastine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Yervoy and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Epinastine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ipilimumab and epinastine hydrochloride (the active ingredients of Yervoy and Epinastine hydrochloride, respectively), and Yervoy and Epinastine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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